Aliaga I L, Miller D L, Wilson H D, Schedl H P
Medical Service, VA Medical Center, Iowa City, IA.
Am J Clin Nutr. 1990 Nov;52(5):867-71. doi: 10.1093/ajcn/52.5.867.
Resection increases villus height and crypt depth of remaining intestine. We examined functional consequences of resection by measuring absorption of strontium and secretion of calcium and magnesium by proximal and distal segments remaining after resecting 70% of mid small intestine. Compared with the transected control group, resection decreased strontium absorption per unit weight of mucosa (specific absorption) in the proximal segment. The decreased specific absorption was compensated by increased mucosal growth in the resected group so that absorption per unit length of segment (per cm) was the same in both groups. Resection increased secretion of calcium and magnesium by 66% per unit weight of mucosa and by 145%/cm in the distal segment. Comparing proximal with distal segments in the resected group, secretion was greater in distal for calcium and in proximal for magnesium. Intestinal resection causes responses in absorption and secretion of divalent cations important in mineral homeostasis.
切除手术会增加剩余肠道的绒毛高度和隐窝深度。我们通过测量切除70%的中小肠后剩余近端和远端肠段对锶的吸收以及钙和镁的分泌，来研究切除手术的功能后果。与横断对照组相比，切除手术降低了近端肠段每单位黏膜重量的锶吸收（比吸收）。切除组中比吸收的降低通过黏膜生长的增加得到了补偿，因此两组每单位肠段长度（每厘米）的吸收量相同。切除手术使远端肠段每单位黏膜重量的钙和镁分泌增加了66%，每厘米增加了145%。在切除组中比较近端和远端肠段，钙的分泌在远端更高，镁的分泌在近端更高。肠道切除会引起对矿物质稳态至关重要的二价阳离子吸收和分泌的反应。
