Department of Urology, University of Cukurova, Faculty of Medicine, Adana, Turkey.
Int Braz J Urol. 2012 Jan-Feb;38(1):122-8. doi: 10.1590/s1677-55382012000100017.
The efficacy of three different analgesic techniques during transrectal ultrasound (TRUS) guided prostate biopsy, including (i) periprostatic blockage (PPB), (ii) intrarectal gel instillation, and (iii) sedoanalgesia were compared.
During a period of five months, 100 consecutive men were enrolled in this study. A 10-point linear visual analogue scale (VAS) was used to assess the pain scores during (VAS 1), immediately after (VAS 2) and one hour after (VAS 3) the needle biopsy procedure. The relationship between the level of pain, prostate volume, age and PSA was determined.
There were no statistically significant differences between the four groups in terms of mean age and PSA values. The pain scores were significantly lower in sedoanalgesia and PPB groups (p = 0.0001). There was no statistically significant difference between the groups in terms of complications.
In this study, it was shown that patient comfort is better and it is possible to get decreased pain scores with PPB or sedoanalgesia. However, PPB is a preferable method in TRUS-guided prostate biopsy since it is much more practical in outpatient clinics.
比较经直肠超声（TRUS）引导下前列腺活检中三种不同镇痛技术的疗效，包括（i）前列腺周围阻滞（PPB）、（ii）直肠内凝胶灌注和（iii）镇静镇痛。
在五个月的时间里，100 名连续男性患者入组本研究。使用 10 分线性视觉模拟评分（VAS）评估针吸活检过程中（VAS1）、即刻后（VAS2）和 1 小时后（VAS3）的疼痛评分。确定疼痛程度、前列腺体积、年龄和 PSA 之间的关系。
在平均年龄和 PSA 值方面，四组之间无统计学差异。在 sedoanalgesia 和 PPB 组中，疼痛评分显著降低（p = 0.0001）。各组之间在并发症方面无统计学差异。
在本研究中，PPB 或 sedoanalgesia 可使患者舒适度提高，疼痛评分降低。然而，由于在门诊中更实用，PPB 是 TRUS 引导下前列腺活检中更优的方法。
