Department of Paediatric Gastroenterology, Hepatology & Nutrition, Addenbrooke's Hospital, Cambridge University, Cambridge, UK.
J Crohns Colitis. 2012 Jun;6(5):550-6. doi: 10.1016/j.crohns.2011.10.014. Epub 2011 Dec 1.
Children with inflammatory bowel disease (IBD) frequently present with small bowel involvement at some stage of their disease. Hence, reliable assessment of the entire small bowel is required in order to adjust treatment accordingly. Recently, magnetic resonance imaging (MRI) of the small bowel in combination with luminal contrast agent delivered via a naso-jejunal tube (MR enteroclysis) is an emerging technique demonstrating good results in adult patients. However, data on its use and benefits in children is limited.
In this study we report our experience on performing small bowel MR enteroclysis (MRE) in children with IBD. Specifically, we reviewed indications, MR findings, advantages and disadvantages of the technique in a tertiary unit.
A total of 34 MRE studies (29 paediatric IBD patients) were retrospectively analysed. All patients underwent upper and lower endoscopy under general anaesthetic (GA) the day before MR imaging was performed. Nasojejunal (NJ)-tube was placed during endoscopy.
Frequently detected findings included small and large bowel wall thickening, small bowel strictures and intestinal lymph node enlargement. Importantly, in all our clinical cases, MRE results were key to making a clinical decision in the given scenario regardless of whether MRE findings were positive or negative.
Within our setup, MR enteroclysis is a well-tolerated, sensitive technique for small bowel imaging, providing detailed information at crucial clinical decision points. Moreover, accurate information then allows appropriate clinical decisions to be made.
儿童炎症性肠病(IBD)患者在疾病的某个阶段常出现小肠受累。因此,需要对整个小肠进行可靠的评估,以便相应地调整治疗方案。最近,磁共振小肠成像(MRI)结合经鼻空肠管(MR 肠造影)腔内对比剂的应用,在成人患者中显示出良好的效果,是一种新兴技术。然而,关于其在儿童中的应用和益处的数据有限。
本研究报告了我们在炎症性肠病儿童中进行小肠 MR 肠造影(MRE)的经验。具体来说,我们在一家三级医疗机构中回顾了该技术的适应证、MR 表现、优点和缺点。
回顾性分析了 34 例 MRE 研究(29 例儿科 IBD 患者)。所有患者均在 MR 成像前一天全身麻醉(GA)下行上、下内镜检查。在结肠镜检查中放置鼻空肠(NJ)管。
经常发现的表现包括小肠和大肠壁增厚、小肠狭窄和肠淋巴结肿大。重要的是,在我们所有的临床病例中,MRE 结果对于在特定情况下做出临床决策至关重要,无论 MRE 结果是阳性还是阴性。
在我们的设置中,MR 肠造影是一种耐受性良好、敏感的小肠成像技术,在关键的临床决策点提供详细的信息。此外,准确的信息可以帮助做出适当的临床决策。