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免疫抑制的肾移植受者中的“三重感染”(真菌、细菌和病毒感染)

"Triple infections" (fungal, bacterial and viral) in immunosuppressed renal transplant recipients.

作者信息

Zazgornik J, Schmidt P, Kopsa H, Thurner J, Deutsch E

出版信息

Int Urol Nephrol. 1979;11(2):145-50. doi: 10.1007/BF02082234.

DOI:10.1007/BF02082234
PMID:224003
Abstract

In a period of 5 years, 8 out of 77 renal transplant patients showed simultaneous fungal, bacterial and viral infections. Candida albicans was found in all cases. The most severe bacterial complications were infections with Klebsiella, Pseudomonas and Staphylococcus aureus. Cytomegalovirus, persistent HBsAg positive hepatitis, herpes zoster, and herpes simplex infections were also found. Seven patients died of bacterial superinfection and miliary tuberculosis. The data presented show that "triple infections" are associated with high mortality and that miliary tuberculosis occurred frequently in immunosuppressed renal transplant recipients.

摘要

在5年的时间里,77例肾移植患者中有8例同时出现真菌、细菌和病毒感染。所有病例均发现白色念珠菌。最严重的细菌并发症是克雷伯菌、铜绿假单胞菌和金黄色葡萄球菌感染。还发现了巨细胞病毒、持续性乙肝表面抗原阳性肝炎、带状疱疹和单纯疱疹感染。7例患者死于细菌二重感染和粟粒性肺结核。所呈现的数据表明,“三重感染”与高死亡率相关,并且粟粒性肺结核在免疫抑制的肾移植受者中频繁发生。

相似文献

1
"Triple infections" (fungal, bacterial and viral) in immunosuppressed renal transplant recipients.免疫抑制的肾移植受者中的“三重感染”(真菌、细菌和病毒感染)
Int Urol Nephrol. 1979;11(2):145-50. doi: 10.1007/BF02082234.
2
[Problems of infections following renal transplantation (author's transl)].肾移植后感染问题(作者译)
Wien Klin Wochenschr. 1975 May 30;87(11):367-71.
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Viral infections in kidney transplant patients immunosuppressed with cyclosporine.接受环孢素免疫抑制治疗的肾移植患者中的病毒感染。
Transplant Proc. 1987 Feb;19(1 Pt 3):2142-9.
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[Complications after kidney transplants. Observations of 147 recipients of homologous transplantations during 1964-72].[肾移植后的并发症。1964年至1972年期间147例同种移植受者的观察结果]
Schweiz Med Wochenschr. 1974 Jun 22;104(25):873-7.
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Infections in renal transplant recipients receiving mycophenolate versus azathioprine-based immunosuppression.接受霉酚酸酯与硫唑嘌呤免疫抑制治疗的肾移植受者的感染情况。
Eur J Clin Microbiol Infect Dis. 2002 Mar;21(3):173-80. doi: 10.1007/s10096-001-0684-y. Epub 2002 Mar 19.
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Primary cytomegalovirus and opportunistic infections. Incidence in renal transplant recipients.原发性巨细胞病毒感染与机会性感染。肾移植受者中的发病率。
JAMA. 1978 Nov 24;240(22):2446-9.
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Viral infections in renal transplant recipients: an evolutionary problem.肾移植受者中的病毒感染:一个进化问题。
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[Mixed infection after renal transplantation (author's transl)].肾移植后的混合感染(作者译)
Wien Klin Wochenschr. 1979 Aug 10;91(15):521-4.
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Infections in solid-organ transplant recipients.实体器官移植受者的感染
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本文引用的文献

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INFECTIOUS PULMONARY DISEASE IN PATIENTS RECEIVING IMMUNOSUPPRESSIVE THERAPY FOR ORGAN TRANSPLANTATION.接受器官移植免疫抑制治疗患者的感染性肺部疾病
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[Experimental fungiemia and fungiuria by oral administration of large amounts of Candida albicans in healthy man (self-experiment)].[健康人经口服大量白色念珠菌诱发实验性真菌血症和真菌尿(自我实验)]
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The role of antibiotics in the pathogenesis of Candidainfections.抗生素在念珠菌感染发病机制中的作用。
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5
Systemic fungal infections complicating renal transplantation and immunosuppressive therapy. Clinical, microbiologic, neurologic and pathologic features.并发肾移植及免疫抑制治疗的系统性真菌感染。临床、微生物学、神经学及病理学特征。
Am J Med. 1967 Jul;43(1):28-38. doi: 10.1016/0002-9343(67)90146-5.
6
[Extracorporeal irradiation in renal rejection reactions (author's transl)].肾移植排斥反应中的体外照射(作者译)
Wien Klin Wochenschr. 1974 Nov 29;86(22):682-6.
7
[Fungal infections in patients on intermittent haemodialysis and following renal transplantation: an epidemiological investigation (author's transl)].间歇性血液透析患者及肾移植后患者的真菌感染:一项流行病学调查(作者译)
Wien Klin Wochenschr. 1974 Sep 6;86(16):456-9.
8
Liver disease in kidney transplant patients receiving azathioprine.接受硫唑嘌呤治疗的肾移植患者中的肝脏疾病
Arch Intern Med. 1973 Jul;132(1):29-37.
9
Hepatitis affecting hemodialysis and transplant patients. Its considerations and consequences.影响血液透析和移植患者的肝炎。其考量因素及后果。
Arch Intern Med. 1973 Jul;132(1):21-8.
10
Aspergillosis in four renal transplant recipients. Diagnosis and effective treatment with amphotericin B.4例肾移植受者的曲霉病。两性霉素B的诊断及有效治疗
Ann Intern Med. 1972 Sep;77(3):383-8. doi: 10.7326/0003-4819-77-3-383.