Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, China.
Org Biomol Chem. 2012 Apr 21;10(15):2950-4. doi: 10.1039/c2ob07192d. Epub 2012 Mar 8.
By employing a chiral bifunctional thiourea-tertiary amine as catalyst, enantioselective Michael addition of a kojic acid derivative to nitro olefins was realised. The reactions afforded the products with good yields (up to 99%) in good enantioselectivities (up to 97% ee). In addition, the absolute configuration of one product was determined.
通过使用手性双功能硫脲-叔胺作为催化剂，实现了洛酸衍生物与硝基烯烃的对映选择性迈克尔加成反应。反应以良好的收率（高达 99%）和良好的对映选择性（高达 97%ee）得到产物。此外，还确定了一个产物的绝对构型。
