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多方面、跨学科生活方式干预对降低心血管疾病风险和改善心血管疾病风险患者生活方式的长期疗效的随机对照试验。

Randomized controlled trial on the long-term efficacy of a multifaceted, interdisciplinary lifestyle intervention in reducing cardiovascular risk and improving lifestyle in patients at risk of cardiovascular disease.

机构信息

Institut de Recherches Cliniques de Montréal, 110 Avenue des Pins Ouest, Montreal, QC, H2W 1R7, Canada.

出版信息

J Behav Med. 2013 Apr;36(2):212-24. doi: 10.1007/s10865-012-9407-3. Epub 2012 Mar 9.

Abstract

The objective of the study was to evaluate the efficacy of an interdisciplinary intervention known as Educoeur in reducing cardiovascular risk and improving health behaviors in people without evidence of cardiovascular disease and to compare the Educoeur program to interventions in a specialized clinic and in usual care family practice. In a parallel, randomized, controlled trial of 185 adults with at least two modifiable cardiovascular risk factors, patients were randomly assigned to either Educoeur, specialized clinic or usual care. Cardiovascular risk, biological and lifestyle measures were assessed at baseline and at 2 years. In Educoeur, measurements were also taken before and after the lifestyle group treatment program. In 12 weeks, patients in Educoeur significantly lowered their cardiovascular risk, weight, body mass index, waist circumference, systolic blood pressure, kilocalories intake and improved their VO2 Max and mental health. Changes remained significant at 2 years. Between group comparisons at 2 years demonstrated that Educoeur was significantly better in reducing cardiovascular risk than interventions in usual care. Together, these results highlight the importance of providing interdisciplinary programs that optimize cardiovascular risk reduction and promote active lifestyles in patients at risk of cardiovascular disease.

摘要

本研究旨在评估一种名为 Educoeur 的跨学科干预措施在降低无心血管疾病证据人群的心血管风险和改善健康行为方面的疗效,并将 Educoeur 方案与专科诊所和常规家庭实践中的干预措施进行比较。在一项针对至少有两个可改变心血管风险因素的 185 名成年人的平行、随机、对照试验中,患者被随机分配到 Educoeur、专科诊所或常规护理组。在基线和 2 年后评估心血管风险、生物学和生活方式指标。在 Educoeur 组中,还在生活方式组治疗方案前后进行了测量。在 12 周内,Educoeur 组患者显著降低了心血管风险、体重、体重指数、腰围、收缩压、热量摄入,并提高了最大摄氧量和心理健康水平。这些变化在 2 年后仍然显著。2 年后的组间比较表明,Educoeur 在降低心血管风险方面明显优于常规护理中的干预措施。综上所述,这些结果强调了提供跨学科方案的重要性,这些方案可以优化心血管风险降低,并促进心血管疾病风险患者积极的生活方式。

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