Suppr超能文献

尿流改道后的代谢性长期并发症

[Metabolic long-term complications after urinary diversion].

作者信息

Stein R, Ziesel C, Frees S, Thüroff J W

机构信息

Abteilung Kinderurologie, Urologische Klinik und Poliklinik, Universitätsmedizin, Johannes Gutenberg-Universität Mainz, Langenbeckstraße 1, 55131, Mainz, Deutschland.

出版信息

Urologe A. 2012 Apr;51(4):507-9, 512-4. doi: 10.1007/s00120-012-2816-7.

Abstract

Metabolic long-term complications and consequences after urinary diversion are somewhat neglected. Subclinical metabolic disturbances are quite common; however, complications are rare. The absorptive surface of the bowel segment is lost for the physiological function of the gastrointestinal tract. Some studies demonstrated that at least some of the absorbent and secreting properties of the bowel are preserved if exposed to urine. For each bowel segment typical complications are reported. Using ileal and/or colon segments, hyperchloremic metabolic acidosis may occur. Studies demonstrated that metabolic effects are not as severe as suspected and could be prevented if a prophylactic treatment is started early.The resection of ileal segments is responsible for malabsorption of vitamin B(12) and bile acid; when using colonic segments, electrolyte disturbances are more common. Careful patient selection, meticulous follow-up and prophylactic treatment are crucial to prevent metabolic complications.

摘要

尿流改道术后的代谢性长期并发症及后果在一定程度上被忽视了。亚临床代谢紊乱相当常见;然而,并发症却很罕见。肠道段的吸收表面丧失了胃肠道的生理功能。一些研究表明,如果肠道暴露于尿液中,其至少部分吸收和分泌特性会得以保留。针对每个肠道段都有典型并发症的报道。使用回肠段和/或结肠段时,可能会发生高氯性代谢性酸中毒。研究表明,代谢影响并不像人们怀疑的那么严重,如果早期开始预防性治疗是可以预防的。回肠段的切除会导致维生素B12和胆汁酸吸收不良;使用结肠段时,电解质紊乱更为常见。仔细的患者选择、细致的随访和预防性治疗对于预防代谢并发症至关重要。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验