Department of Pediatric Cardiology and GUCH Unit, Policlinico San Donato IRCCS, Via Morandi, 30, 20097 San Donato Milanese, Italy.
Expert Rev Med Devices. 2012 Mar;9(2):123-30. doi: 10.1586/erd.12.2.
Aortic coarctation comprises approximately 7% of all known congenital heart defects. Surgery and balloon angioplasty have been performed for many years but are associated with a significant incidence of recoarctation and aneurysm formation. Although bare-stent implantation decreases the incidence of recoarctation, the risk of aortic dissection or aneurysm formation is not eliminated. Described initially to treat patients with coexistent aneurysm of the aortic wall, we currently believe that covered-stent implantation for aortic coarctation should play a more important role. Our increasing experience from expanding their indication to deal with complications from previous interventions, associated defects or particular anatomical situations has led us to conclude that most of cases of aortic coarctation in adolescents and adults should be treated by the implantation of covered stents.
主动脉缩窄约占所有已知先天性心脏缺陷的 7%。多年来,已经进行了手术和球囊血管成形术,但它们与再狭窄和动脉瘤形成的发生率显著相关。虽然裸支架植入术可降低再狭窄的发生率,但并不能消除主动脉夹层或动脉瘤形成的风险。最初描述为治疗同时存在的主动脉壁动脉瘤的患者,我们目前认为,带膜支架植入术治疗主动脉缩窄应发挥更重要的作用。我们的经验不断增加,将适应证扩大到处理先前干预、相关缺陷或特定解剖情况引起的并发症,这使我们得出结论,大多数青少年和成年患者的主动脉缩窄应通过植入带膜支架来治疗。