Department of Human Genetics, McGill University/MNI, Montreal, QC H3A 2B4, Canada.
Cell Metab. 2012 Mar 7;15(3):271-2. doi: 10.1016/j.cmet.2012.02.009.
The complexes of the mitochondrial respiratory chain assemble into higher-order structures called supercomplexes or respirasomes that are thought to be important in channeling electron flow and controlling ROS production. A number of recent papers identify the first protein factors necessary for supercomplex assembly and stability.
线粒体呼吸链的复合物组装成更高阶的结构,称为超复合体或呼吸体,被认为在电子流的传导和控制 ROS 产生方面很重要。最近的一些论文确定了组装和稳定超复合体所需的第一批蛋白质因子。