Research Imaging Institute, University of Texas Health Science Center San Antonio, San Antonio, TX 78229, USA.
Neuroimage. 2012 May 15;61(1):314-22. doi: 10.1016/j.neuroimage.2012.02.068. Epub 2012 Mar 3.
Auditory feedback is important for the control of voice fundamental frequency (F0). In the present study we used neuroimaging to identify regions of the brain responsible for sensory control of the voice. We used a pitch-shift paradigm where subjects respond to an alteration, or shift, of voice pitch auditory feedback with a reflexive change in F0. To determine the neural substrates involved in these audio-vocal responses, subjects underwent fMRI scanning while vocalizing with or without pitch-shifted feedback. The comparison of shifted and unshifted vocalization revealed activation bilaterally in the superior temporal gyrus (STG) in response to the pitch shifted feedback. We hypothesize that the STG activity is related to error detection by auditory error cells located in the superior temporal cortex and efference copy mechanisms whereby this region is responsible for the coding of a mismatch between actual and predicted voice F0.
听觉反馈对于控制声音基频（F0）非常重要。在本研究中，我们使用神经影像学来确定负责声音感觉控制的大脑区域。我们使用了一种音高移位范式，其中受试者通过 F0 的反射性变化来响应语音音高听觉反馈的改变或移位。为了确定这些音频-语音反应涉及的神经基质，受试者在发声时或不发声时进行 fMRI 扫描带有或不带有音高移位反馈。移位和未移位发声的比较显示，双侧上颞回（STG）在响应音高移位反馈时激活。我们假设 STG 活动与位于上颞皮质中的听觉误差细胞的误差检测有关，以及传出复制机制，该机制负责对实际和预测的语音 F0 之间的不匹配进行编码。
