Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA.
J Occup Environ Med. 2012 Mar;54(3):310-7. doi: 10.1097/JOM.0b013e31823fe098.
To evaluate the incidence of post-hire asthma (PHA) among insect-rearing workers, defined as asthma, the symptoms of which appeared after hire at the current workplace.
We surveyed the health of workers at three insect-rearing facilities and an associated office facility. We calculated the incidence and estimated hazard ratios for PHA.
Post-hire asthma incidence in 157 insect-rearing workers was 16.2 per 1000 person-years compared with 9.2 per 1,000 person-years in 70 office workers. Workers with predominant exposure to Lepidoptera had an incidence of 26.9 per 1000 person-years and a hazard ratio of 5.5 (95% confidence interval: 1.6 to 23.9) adjusted for sex, race, and parental asthma. In contrast, the presence of specific immunoglobulin E to Lepidoptera antigens was not associated with PHA.
Insect-rearing workers had a high incidence of PHA, primarily accounted for by workplace exposure to Lepidoptera.
评估饲养昆虫工人的雇佣后哮喘（PHA）发病率，定义为在当前工作场所雇佣后出现的哮喘症状。
我们调查了三个昆虫饲养设施和一个相关办公设施的工人健康状况。我们计算了 PHA 的发病率和估计危险比。
与 70 名办公室工人每 1000 人年 9.2 例相比，157 名饲养昆虫工人的雇佣后哮喘发病率为每 1000 人年 16.2 例。主要暴露于鳞翅目昆虫的工人发病率为每 1000 人年 26.9 例，调整性别、种族和父母哮喘后危险比为 5.5（95%置信区间：1.6 至 23.9）。相比之下，特定免疫球蛋白 E 对鳞翅目抗原的存在与 PHA 无关。
饲养昆虫的工人 PHA 发病率很高，主要是由于工作场所接触鳞翅目昆虫所致。
