Department of Neurosurgery, Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, India.
Neurol India. 2012 Jan-Feb;60(1):90-3. doi: 10.4103/0028-3886.93611.
Intracranial germ cell tumors constitute a unique group of tumors, more often reported from the Asian region. Amongst them, the non-germinomatous variety occurs with a lesser frequency than the germinomatous variety. We report two children with mixed germ cell tumors with unusual clinical presentations: Central diabetes insipidus and recent-onset oculomotor palsy mimicking pituitary apoplexy. Unlike in adults, suprasellar lesions with a pituitary apoplexy-like picture in the pediatric age group may suggest a possibility of a mixed germ cell tumor.
颅内生殖细胞肿瘤构成了一组独特的肿瘤,更多见于亚洲地区。其中,非生殖细胞瘤比生殖细胞瘤少见。我们报告了两例具有不常见临床表现的混合生殖细胞瘤患儿:中枢性尿崩症和新近发生的动眼神经麻痹,类似于垂体卒中。与成人不同,在儿科年龄组中,具有垂体卒中样表现的鞍上病变可能提示存在混合生殖细胞瘤的可能性。