迟发性 Behcet 病患者的人口统计学、临床和眼部特征。
Demographic, clinical, and ocular features in patients with late-onset Behçet disease.
机构信息
Department of 1st Eye Clinic, Ankara Training and Research Hospital, Ministry of Health, Ankara, Turkey.
出版信息
Ocul Immunol Inflamm. 2012 Apr;20(2):119-24. doi: 10.3109/09273948.2012.655882.
PURPOSE
To evaluate demographic, clinical, and ocular features of patients with late-onset Behçet disease (BD).
METHODS
The study included 26 patients with late-onset BD. Onset of their first symptoms was before age 40. They fulfilled the diagnostic criteria after age 40. Patients were divided into 2 groups: group 1 had uveitis and group 2 had no uveitis. Clinical and demographic features of the groups were compared. Ocular manifestations in group 1 were also evaluated.
RESULTS
Fourteen patients (53.8%) had uveitis and 12 patients (46.2%) had no ocular involvement. The incidence of genital ulcer was higher in group 1. Twelve patients (18 eyes) had anterior uveitis and 2 patients (4 eyes) had panuveitis. The incidence of anterior uveitis was higher in females. The incidence of panuveitis was higher in males.
CONCLUSIONS
As compared to potentially devastating posterior uveitis, anterior uveitis is more often encountered in patients with late-onset BD. Hence, with respect to ocular involvement, the prognosis is better.
目的
评估迟发性 Behçet 病（BD）患者的人口统计学、临床和眼部特征。
方法
本研究纳入了 26 例迟发性 BD 患者。他们的首发症状发生在 40 岁之前，40 岁以后才符合诊断标准。患者分为两组：组 1 为葡萄膜炎组，组 2 为非葡萄膜炎组。比较两组的临床和人口统计学特征。还评估了组 1 的眼部表现。
结果
14 例（53.8%）患者有葡萄膜炎，12 例（46.2%）患者无眼部受累。组 1 的生殖器溃疡发生率较高。12 例（18 只眼）患者有前葡萄膜炎，2 例（4 只眼）患者有全葡萄膜炎。女性中前葡萄膜炎的发生率较高，而男性中全葡萄膜炎的发生率较高。
结论
与可能造成严重后果的后葡萄膜炎相比，迟发性 BD 患者中更常发生前葡萄膜炎。因此，就眼部受累而言，预后较好。
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