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自发性右冠状动脉夹层:导致一名36岁女性心肌梗死

Spontaneous right coronary artery dissection: causing myocardial infarction in a 36-year-old woman.

作者信息

Klein Joshua, Hakimian Justin, Makaryus Amgad N

机构信息

Department of Cardiology, North Shore University Hospital, Manhasset, New York 11030, USA.

出版信息

Tex Heart Inst J. 2012;39(1):95-8.

Abstract

Spontaneous coronary artery dissection is a rather rare cause of myocardial infarction, chest pain, and sudden death. Since the condition was first described in 1931, fewer than 200 cases have been reported in the medical literature. There are currently no known direct causes of this condition, although some correlations have been noted. Many patients are women in the peripartum period or of childbearing age, with few or no risk factors for coronary artery disease. Other associations include contraceptive use and connective-tissue disorders, Ehlers-Danlos and Marfan syndromes, and polyarteritis nodosa. Most of the reported dissections have occurred in the left anterior descending coronary artery. Herein, we report the case of a 36-year-old woman who presented at our institution with an acute ST-elevation myocardial infarction secondary to a spontaneous dissection of the right coronary artery. Thrombectomy and stenting resolved the occlusion of the artery, and the patient was discharged from the hospital on medical therapy. We discuss the pathophysiology, presentation, and treatment of this rare and often fatal condition.

摘要

自发性冠状动脉夹层是心肌梗死、胸痛和猝死的一种相当罕见的病因。自1931年首次描述该病症以来,医学文献中报道的病例不到200例。目前尚不清楚该病症的直接病因,不过已注意到一些相关性。许多患者是围产期或育龄期女性,几乎没有或没有冠状动脉疾病的危险因素。其他相关因素包括使用避孕药和结缔组织疾病、埃勒斯-当洛综合征和马方综合征以及结节性多动脉炎。大多数报道的夹层发生在左前降支冠状动脉。在此,我们报告一例36岁女性患者,她因右冠状动脉自发性夹层导致急性ST段抬高型心肌梗死前来我院就诊。血栓切除术和支架置入术解决了动脉闭塞问题,患者经药物治疗后出院。我们讨论了这种罕见且常致命病症的病理生理学、临床表现和治疗方法。

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Spontaneous Coronary Artery Dissection with Cardiac Tamponade.自发性冠状动脉夹层伴心脏压塞
Tex Heart Inst J. 2015 Oct 1;42(5):479-82. doi: 10.14503/THIJ-14-4260. eCollection 2015 Oct.

本文引用的文献

6
Spontaneous coronary artery dissection: the clinical spectrum.
Angiology. 2002 Jan-Feb;53(1):89-93. doi: 10.1177/000331970205300112.

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