Hopp Christa, Goebel William, Hildebolt Charles, Rotter Bruce
Operative Section, Restorative Department, Southern Illinois University School of Dental Medicine in Alton, USA
Gen Dent. 2012 Mar-Apr;60(2):e69-73.
Benzocaine, the most commonly used topical anesthetic in dentistry, often fails to eliminate the pain associated with injections. One type of anesthetic used frequently in medicine with success is tetracaine, but minimal research has been done regarding the application of tetracaine in dentistry. This study sought to evaluate the effectiveness and safety of tetracaine anesthetic paste (TAP), a newly formulated topical anesthetic. For this study, TAP was applied to the maxillary mucobuccal fold of one side of the arch and benzocaine paste was applied to the opposite side prior to injection of anesthetic. Patients then reported the level of pain experienced on each side and were evaluated for any adverse reactions. The results showed no difference in effectiveness between TAP and benzocaine paste, and no adverse reactions were reported. Because of the safety and effectiveness of tetracaine extraorally, further research is warranted on its intraoral use.
苯佐卡因是牙科中最常用的局部麻醉剂，但它常常无法消除注射带来的疼痛。丁卡因是医学上常用且有效的一种麻醉剂，但关于丁卡因在牙科中的应用研究极少。本研究旨在评估一种新配制的局部麻醉剂——丁卡因麻醉膏（TAP）的有效性和安全性。在本研究中，在注射麻醉剂之前，将TAP涂于牙弓一侧的上颌黏膜颊褶处，将苯佐卡因膏涂于另一侧。然后患者报告每一侧所经历的疼痛程度，并接受不良反应评估。结果显示TAP和苯佐卡因膏在有效性上没有差异，且未报告有不良反应。由于丁卡因在口腔外的安全性和有效性，有必要对其在口腔内的使用进行进一步研究。
