Department of Psychology, The University of Arizona, Tucson, AZ 85721-0068, USA.
Biol Psychol. 2012 Apr;90(1):105-11. doi: 10.1016/j.biopsycho.2012.02.019. Epub 2012 Mar 3.
Low cardiac vagal control (CVC) has been associated with state and trait anxiety and anxiety spectrum disorders. Studies indicate that diagnosis and treatments for breast cancer may be associated with anxiety. The current study examined whether CVC prospectively predicted a trajectory of change in anxiety following breast cancer diagnosis. Forty-three women diagnosed with non-metastatic breast cancer completed the Taylor Manifest Anxiety Scale and the Perceived Stress Scale, and a 5-min resting electrocardiographic (ECG) segment was recorded. Self-report measures were completed approximately every 3 months for a year. Respiratory sinus arrhythmia (RSA) significantly predicted the trajectory of change in anxiety over the follow-up period: participants with higher baseline RSA evidenced decreasing anxiety, whereas those with lower baseline RSA had increasing anxiety. These results are consistent with the hypothesis that CVC facilitates the modulation of anxiety in women coping with significant stressors of breast cancer diagnosis and treatment.
低心脏迷走神经控制（CVC）与状态和特质焦虑以及焦虑谱系障碍有关。研究表明，乳腺癌的诊断和治疗可能与焦虑有关。本研究旨在探讨 CVC 是否可以预测乳腺癌诊断后焦虑变化的轨迹。43 名被诊断为非转移性乳腺癌的女性完成了泰勒显性焦虑量表和感知压力量表，同时记录了 5 分钟的静息心电图（ECG）片段。自我报告量表大约每 3 个月完成一次，为期一年。呼吸窦性心律失常（RSA）显著预测了随访期间焦虑变化的轨迹：基线 RSA 较高的参与者焦虑程度降低，而基线 RSA 较低的参与者焦虑程度增加。这些结果与假设一致，即 CVC 有助于调节女性应对乳腺癌诊断和治疗的重大压力源时的焦虑。
