药物动力学与人工肾
Drug kinetics and artificial kidneys.
作者信息
Gibson T B, Nelson H A
出版信息
Clin Pharmacokinet. 1977 Nov-Dec;2(6):403-26. doi: 10.2165/00003088-197702060-00002.
Abstract
The factors affecting solute movement across the membrane during haemodialysis are well understood. Likewise the mathematics of drug kinetics are well described. However, studies of the effects of artificial kidneys on drug kinetics have often been limited by a lack of attention to proper methods of calculating solute clearance by the artificial kidney.
摘要
血液透析过程中影响溶质跨膜转运的因素已为人熟知。同样，药物动力学的数学原理也有详尽描述。然而，关于人工肾对药物动力学影响的研究常常因未充分关注人工肾溶质清除率的恰当计算方法而受到限制。
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