Department of Medicine, University of Calgary, Calgary, Alberta, Canada.
Epidemiol Infect. 2013 Jan;141(1):174-80. doi: 10.1017/S0950268812000428. Epub 2012 Mar 15.
Although community-onset bloodstream infection (BSI) is recognized as a major cause of morbidity and mortality, its epidemiology has not been well defined in non-selected populations. We conducted population-based laboratory surveillance in the Victoria area, Canada during 1998-2005 in order to determine the burden associated with community-onset BSI. A total of 2785 episodes were identified for an overall annual incidence of 101·2/100,000. Males and the very young and the elderly were at highest risk. Overall 1980 (71%) episodes resulted in hospital admission for a median length of stay of 8 days; the total days of acute hospitalization associated with community-onset BSI was 28 442 days or 1034 days/100,000 population per year. The in-hospital case-fatality rate was 13%. Community-onset BSI is associated with a major burden of illness. These data support ongoing and future preventative and research efforts aimed at reducing the major impact of these infections.
虽然社区获得性血流感染(BSI)被认为是发病率和死亡率的主要原因,但在非选择性人群中,其流行病学尚未得到很好的定义。我们在加拿大维多利亚地区进行了基于人群的实验室监测,以确定与社区获得性 BSI 相关的负担。在 1998 年至 2005 年期间共确定了 2785 例,总发病率为 101.2/100,000。男性、非常年幼和年老的人风险最高。总体而言,1980 例(71%)导致住院治疗,中位住院时间为 8 天;与社区获得性 BSI 相关的急性住院总天数为 28442 天或每年每 100,000 人 1034 天。住院病死率为 13%。社区获得性 BSI 与重大疾病负担有关。这些数据支持持续和未来的预防和研究工作,旨在减少这些感染的重大影响。