Laupland Kevin B, Schønheyder Henrik C, Kennedy Karina J, Lyytikäinen Outi, Valiquette Louis, Galbraith John, Collignon Peter, Church Deirdre L, Gregson Daniel B, Kibsey Pamela
Department of Medicine, Laboratory Medicine, University of Calgary and Calgary Laboratory Services, Calgary, Alberta, Canada.
BMC Res Notes. 2009 Jul 22;2:146. doi: 10.1186/1756-0500-2-146.
Bloodstream infections are frequent causes of human illness and cause major morbidity and death. In order to best define the epidemiology of these infections and to track changes in occurrence, adverse outcome, and resistance rates over time, population based methodologies are optimal. However, few population-based surveillance systems exist worldwide, and because of differences in methodology inter-regional comparisons are limited. In this report we describe the rationale and propose first practical steps for developing an international collaborative approach to the epidemiologic study and surveillance for bacteremia.
The founding collaborative participants represent six regions in four countries in three continents with a combined annual surveillance population of more than 8 million residents.
Future studies from this collaborative should lead to a better understanding of the epidemiology of bloodstream infections.
血流感染是人类疾病的常见病因，可导致严重发病和死亡。为了最准确地界定这些感染的流行病学特征，并追踪其发生率、不良后果及耐药率随时间的变化，基于人群的方法是最佳选择。然而，全球范围内基于人群的监测系统很少，并且由于方法学上的差异，区域间比较受到限制。在本报告中，我们阐述了开展一项关于菌血症流行病学研究及监测的国际协作方法的基本原理，并提出了初步的实际步骤。
参与协作的创始成员代表了三大洲四个国家的六个地区，每年监测的总人口超过800万居民。
来自该协作组织的未来研究应能增进对血流感染流行病学的了解。
