Department of Surgery, Paracelsus Private Medical University, Salzburg, Austria.
Semin Liver Dis. 2012 Feb;32(1):80-91. doi: 10.1055/s-0032-1306428. Epub 2012 Mar 13.
Nonalcoholic steatohepatitis (NASH) is a stage of nonalcoholic fatty liver disease (NAFLD), and in most patients, is associated with obesity and the metabolic syndrome. The current best treatment of NAFLD and NASH is weight reduction with the current options being life style modifications, with or without pharmaceuticals, and bariatric surgery. Bariatric surgery is an effective treatment option for individuals who are severely obese (body mass index ≥ 35 kg/m(2)), and provides for long-term weight loss and resolution of obesity-associated diseases in most patients. Regression and/or histologic improvement of NASH have been documented after bariatric surgery. We review the available literature reporting on the impact of the various bariatric surgery techniques on NASH.
非酒精性脂肪性肝炎（NASH）是一种非酒精性脂肪性肝病（NAFLD）的阶段，在大多数患者中，与肥胖和代谢综合征相关。目前，NAFLD 和 NASH 的最佳治疗方法是减肥，目前的选择是生活方式的改变，包括或不包括药物治疗，以及减肥手术。减肥手术是一种有效的治疗方法，适用于严重肥胖的个体（体重指数≥35kg/m2），并为大多数患者提供长期的体重减轻和解决与肥胖相关的疾病。减肥手术后已经记录到 NASH 的消退和/或组织学改善。我们回顾了现有的文献，报告了各种减肥手术技术对 NASH 的影响。
