Peng He, Zhao Lu-hang
Department of Biochemistry and Molecular Biology, Zhejiang University School of Medicine, Hangzhou 310058, China.
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2012 Jan;41(1):117-22. doi: 10.3785/j.issn.1008-9292.2012.01.020.
The olfactory perception is the process that the olfactory receptor is activated by odorous molecules, which induce the transduction of signal in the cell and the chemical information is transduced into electrical impulses. After the changed signal is transmitted to the brain, the whole perception process completes. OR gene belongs to the multigene family. The coded olfactory receptor proteins belong to the G-protein-coupled receptor (GPCR) superfamily and therefore are invariably seven-transmembrane domain(7TM) protein. Olfactory receptor protein plays an important role in olfactory perception and signal transduction process.
嗅觉感知是指嗅觉受体被气味分子激活的过程，气味分子诱导细胞内信号转导，化学信息被转化为电冲动。变化后的信号传递到大脑后，整个感知过程完成。嗅觉受体基因（OR基因）属于多基因家族。编码的嗅觉受体蛋白属于G蛋白偶联受体（GPCR）超家族，因此均为七跨膜结构域（7TM）蛋白。嗅觉受体蛋白在嗅觉感知和信号转导过程中起重要作用。
