Piérard-Franchimont C, Piérard G E
CHR hutois, Service de Dermatologie, Huy.
Rev Med Liege. 2012 Jan;67(1):44-50.
Primary cicatricial alopecias (PCA) result from the inflammatory destruction of the hair follicle, followed by its replacement by a fibrotic streamer. The involvement of multipotent stem cells of the hair follicle is possible through a transdifferentiation pathway. The diagnosis relies on clinico-pathologic correlations. PCA are classified as the neutrophilic, lymphocytic and mixed types. Each of these groups gather specific disorders including folliculitis decalvans, dissecting folliculitis of the scalp, erosive pustulosis of the scalp, keloidal acne of the nape, frontal fibrosing alopecia, lichen planopilaris and lupus erythematosus.
原发性瘢痕性脱发（PCA）是由毛囊的炎性破坏引起的，随后被纤维化条索所取代。毛囊多能干细胞可能通过转分化途径参与其中。诊断依赖于临床病理相关性。PCA分为嗜中性、淋巴细胞性和混合型。这些组中的每一组都包含特定的疾病，包括脱发性毛囊炎、头皮穿掘性毛囊炎、头皮糜烂性脓疱病、项部瘢痕疙瘩性痤疮、额部纤维性脱发、扁平苔藓样毛发扁平苔藓和红斑狼疮。
