[急性髓系白血病-M1中的结膜髓系肉瘤]
[Conjunctival myeloid sarcoma in acute myeloblastic leukemia-M1].
作者信息
Méndez-Cepeda P, Millán-Rodríguez A C, Dios E, Alvarez C, Sevillano C
机构信息
Servicio de Oftalmología, Complexo Hospitalario de Pontevedra, Pontevedra, España.
出版信息
Arch Soc Esp Oftalmol. 2012 Mar;87(3):79-81. doi: 10.1016/j.oftal.2011.07.012. Epub 2011 Dec 27.
CLINICAL CASE
A 69-year-old man with a history of acute myeloblastic leukemia-M1 presented with bilateral conjunctival injection. Ophthalmological examination revealed lesions located at the upper tarsal conjunctiva of the right eye and lower tarsal conjunctiva of both eyes. Histological and immunohistochemical studies confirmed conjunctival myeloid sarcoma. The patient died due to multiorgan failure three months later.
DISCUSSION
Extramedullary recurrence of leukemia can appear as an ocular manifestation that brings about a recurrence of the leukemia, leading to a poor prognosis.
临床病例
一名69岁男性，有急性髓系白血病M1病史，出现双侧结膜充血。眼科检查发现病变位于右眼上睑结膜和双眼下睑结膜。组织学和免疫组织化学研究证实为结膜髓系肉瘤。三个月后，患者因多器官功能衰竭死亡。
讨论
白血病的髓外复发可表现为眼部表现，导致白血病复发，预后不良。
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