Hong Esther S, Longmuir Susannah Q, Goins Kenneth M
University of Iowa Hospitals & Clinics, Department of Ophthalmology, Iowa City, IA, USA.
J AAPOS. 2011 Oct;15(5):504-5. doi: 10.1016/j.jaapos.2011.06.003.
A 10-year-old girl presented with a 2-week history of an elevated, red conjunctival mass. She was in remission from acute myeloid leukemia (AML) and had two recurrences. Biopsy revealed a conjunctival myeloid sarcoma, an extramedullary lesion composed of cells of myeloid lineage that may present in children and adults, most commonly in the lymph nodes, skin, and subcutaneous tissues; it is less likely in ocular tissue. In patients with a history of AML, a new myeloid sarcoma is considered a relapse. To the best of our knowledge, this is the first case of a conjunctival myeloid sarcoma heralding a recurrence of an aggressive form of AML in a child.
一名10岁女孩出现结膜肿物隆起、发红,病程2周。她曾患急性髓系白血病(AML),目前处于缓解期,且有两次复发。活检显示为结膜髓系肉瘤,这是一种由髓系细胞构成的髓外病变,可发生于儿童和成人,最常见于淋巴结、皮肤和皮下组织;发生于眼部组织的可能性较小。有AML病史的患者,新出现的髓系肉瘤被视为复发。据我们所知,这是首例结膜髓系肉瘤预示儿童侵袭性AML复发的病例。