Wilson Gregory, Folzenlogen Darcy D
University of Missouri School of Medicine, Division of Immunology and Rheumatology, USA.
Mo Med. 2012 Jan-Feb;109(1):69-74.
The spondyloarthropathies (SpA) are a group of inflammatory rheumatic diseases affecting the spine, peripheral joints and nonarticular structures. Often referred to as "seronegative" due to the absence of rheumatoid factor, SpA include ankylosing spondylitis (AS), reactive arthritis (ReA), enteropathic (IBD) associated arthritis, psoriatic arthritis (PsA), as well as undifferentiated, and juvenile SpA. A broad and overlapping spectrum of disease presentations creates difficulties in determining an initial diagnosis. In the last 10 years treatment options have expanded.
脊柱关节炎（SpA）是一组影响脊柱、外周关节和非关节结构的炎性风湿性疾病。由于缺乏类风湿因子，SpA常被称为“血清阴性”，包括强直性脊柱炎（AS）、反应性关节炎（ReA）、肠病性（IBD）关节炎、银屑病关节炎（PsA），以及未分化型和青少年SpA。广泛且重叠的疾病表现谱给确定初始诊断带来困难。在过去十年中，治疗选择有所增加。
