Commissariat à l'Energie Nucléaire, Institut de Biologie Structurale, Grenoble, France.
Microb Drug Resist. 2012 Jun;18(3):256-60. doi: 10.1089/mdr.2011.0236. Epub 2012 Mar 20.
To make progress in understanding peptidoglycan metabolism, we will reconstitute in vitro the assembly process and the molecular machineries that carry out this formidable task. We review here the reports of isolation of complexes comprising penicillin-binding proteins (PBPs), the enzymes that synthesize the peptidoglycan from its lipid-linked precursor.
为了在理解肽聚糖代谢方面取得进展，我们将体外重建组装过程和执行这一艰巨任务的分子机械。在这里，我们回顾了关于分离包含青霉素结合蛋白（PBPs）的复合物的报告，这些酶从其脂连接前体合成肽聚糖。
