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埃及患者腹部包虫囊肿病诊断与治疗中的超声引导双针法:临床及超声随访

Echoguided pair technique in diagnosis and treat-ment of abdominal hydatid cystic disease in Egyptian patients: clnical and ultrasonographic follow up.

作者信息

El Kady Nabeel, Ramzy Iman, Hanan Hasan A El-Garem, Haleem Abdel, El-Bahnasawy Mamdouh M

机构信息

Department of Tropical Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt.

出版信息

J Egypt Soc Parasitol. 2011 Dec;41(3):527-42.

Abstract

The introduction of the percutaneous puncture, aspiration, injection of scolecidal agent and reaspiration (PAIR) technique is gaining an increasing acceptance in diagnosis and treatment of abdominal cystic hydatid disease (CHD). Thirty-three patients (12 male & 21 female with age between 15 and 70 years) had 46 cysts in liver, spleen and kidneys (75.7%, 18.2% & 6.1% respectively). Puncture, aspiration, injection of 95% sterile alcohol for 20 minutes and reaspiration (PAIR) was used for treatment of hydatid cysts of different types and sizes. Follow up both clinically and ultrasonographically was done over a period of 2 years. The commonest ultrasound picture was type la (overall echofree) in 80.4%, commonly in the liver (75.7%) mainly in the right lobe (88%). Improvement of symptoms had occurred its 85% within 3 weeks. As regards ultrasound follow up of 41 non-complicated cysts within the 1st six months, was disappearance of 5 cysts, 34 reduced in size and 36 showed different grades of solidification. After 1.5 year 10 more cysts disappeared while the pseudotumour appearance was shown in remaining 26 cysts. Ultrasound follow up of the 5 infected cysts revealed complete cure within a period of 8-16 weeks in 4 of them. The last patient discontinued drainage therapy and was referred to surgery. This makes ultrasound cure reaching 97%. Minor complications were skin reaction only in 2 patients (6%). No fatal anaphylaxis cyst recurrence or rupture into the peritoneal cavity or bleeding from renal or splenic puncturing. PAIR technique under ultrasonographic guidance is the first choice method for treatment of abdominal CHD especially in the developing countries and inoperable hydatid cysts.

摘要

经皮穿刺、抽吸、注射杀头节剂及再次抽吸(PAIR)技术在腹部囊性包虫病(CHD)的诊断和治疗中越来越被广泛接受。33例患者(男12例,女21例,年龄15至70岁)肝脏、脾脏和肾脏有46个囊肿(分别占75.7%、18.2%和6.1%)。采用穿刺、抽吸、注射95%无菌酒精20分钟及再次抽吸(PAIR)治疗不同类型和大小的包虫囊肿。在2年时间内进行了临床和超声随访。最常见的超声图像为la型(完全无回声),占80.4%,常见于肝脏(75.7%),主要在右叶(88%)。85%的患者症状在3周内有所改善。关于前6个月内41个非复杂性囊肿的超声随访,5个囊肿消失,34个囊肿缩小,36个囊肿显示不同程度的实性变。1.5年后,又有10个囊肿消失,其余26个囊肿呈现假肿瘤外观。对5个感染性囊肿的超声随访显示,其中4个在8至16周内完全治愈。最后1例患者停止引流治疗并转诊至外科手术。这使得超声治愈率达到97%。轻微并发症仅2例患者(6%)出现皮肤反应。无致命性过敏反应、囊肿复发、破裂入腹腔或肾或脾穿刺出血。超声引导下的PAIR技术是治疗腹部CHD的首选方法,尤其适用于发展中国家及无法手术的包虫囊肿。

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