Rogeness G A, Cepeda C, Macedo C A, Fischer C, Harris W R
Department of Psychiatry, University of Texas Health Science Center, San Antonio 79294-7792.
Psychiatry Res. 1990 Aug;33(2):199-206. doi: 10.1016/0165-1781(90)90074-f.
Heart rate and blood pressure of children and adolescents admitted to a psychiatric hospital were compared among those diagnosed conduct disorder, major depressive disorder, and separation anxiety disorder. Subjects with conduct disorder had a lower heart rate compared to subjects without a conduct disorder diagnosis; and subjects with separation anxiety disorder had higher heart rate and systolic blood pressure compared to subjects without an anxiety disorder diagnosis. Subjects with major depressive disorder had higher systolic blood pressure than subjects with conduct disorder but no difference in heart rate. The findings are consistent with conduct disorder being associated with decreased noradrenergic function and anxiety/depressive disorder being associated with increased noradrenergic function.
对入住精神病医院的儿童和青少年进行研究,比较了被诊断为品行障碍、重度抑郁症和分离焦虑症的患者的心率和血压。与未被诊断为品行障碍的患者相比,患有品行障碍的患者心率较低;与未被诊断为焦虑症的患者相比,患有分离焦虑症的患者心率和收缩压较高。患有重度抑郁症的患者收缩压高于患有品行障碍的患者,但心率无差异。这些发现与品行障碍与去甲肾上腺素能功能降低有关,以及焦虑/抑郁症与去甲肾上腺素能功能增加有关的观点一致。