Gozzi G, Stacul F, Bassini A, Macorig D, Ukovich W
Istituto di Radiologia, Università, Ospedale di Cattinara, Trieste.
Radiol Med. 1990 Oct;80(4):477-82.
Data concerning patients who underwent mammography and breast ultrasonography and then breast surgery were collected and analyzed with a computer archive system. In previous papers the authors reported both design and implementation of the computer archive and analyzed the results concerning uncontrolled collected data; in the present paper data concerning controlled cases are evaluated, distinguishing between symptomatic and asymptomatic cases. Asymptomatic patients represented 92% of the whole evaluated population. However only one third of the patients who underwent surgery for breast cancer was included in this group. Breast cancer was discovered in 65% of the patients who underwent diagnostic procedures and then surgery because of a palpable nodule. This percentage was lower (52%) in asymptomatic patients. Mammographic accuracy was about 90% in symptomatic patients and 81% in asymptomatic patients. Breast ultrasonography was performed as a subsequent step and always detected the lesion when palpable. Its sensitivity was 86% in asymptomatic patients. In patients who underwent surgery the false positive rate for cancer was higher with ultrasonography (59%) than with mammography (45%). Focal dysplasis were responsible for the majority of false positive diagnoses with both procedures. However, the false positive rate is low referring to the whole investigated population and is reshuffled by guided bioptic procedures. Ultrasonography was a useful tool when mammography had limitations: in fact ultrasonography detected a focal lesion in all patients with a surgically proven cancer and a previous negative mammography. The sets of data available from the continuous updating of the computer archive immediately clarified the differences between symptomatic and asymptomatic patients and stressed the diagnostic capabilities of the different procedures.
收集了接受乳腺钼靶摄影和乳腺超声检查然后进行乳腺手术的患者的数据,并使用计算机存档系统进行分析。在之前的论文中,作者报告了计算机存档的设计和实施情况,并分析了有关未控制收集数据的结果;在本文中,对有关对照病例的数据进行了评估,区分了有症状和无症状病例。无症状患者占整个评估人群的92%。然而,该组仅包括三分之一接受乳腺癌手术的患者。在因可触及结节而接受诊断性检查然后手术的患者中,65%发现了乳腺癌。在无症状患者中,这一比例较低(52%)。有症状患者的乳腺钼靶摄影准确率约为90%,无症状患者为81%。乳腺超声检查作为后续步骤进行,当可触及病变时总能检测到。其在无症状患者中的敏感性为86%。在接受手术的患者中,超声检查的癌症假阳性率(59%)高于乳腺钼靶摄影(45%)。两种检查方法中,局灶性发育异常是导致大多数假阳性诊断的原因。然而,就整个调查人群而言,假阳性率较低,并且通过引导活检程序进行了调整。当乳腺钼靶摄影存在局限性时,超声检查是一种有用的工具:事实上,超声检查在所有经手术证实患有癌症且之前乳腺钼靶摄影为阴性的患者中均检测到了局灶性病变。计算机存档不断更新提供的数据集立即明确了有症状和无症状患者之间的差异,并强调了不同检查方法的诊断能力。