Department of Surgery, Aga Khan University, Karachi, Pakistan.
Br J Surg. 2012 Jan;99 Suppl 1:155-64. doi: 10.1002/bjs.7735.
The aim of this study was to investigate trends in the practice of selective non-operative management (SNOM) for penetrating abdominal injury (PAI) and to determine factors associated with its failure.
The National Trauma Data Bank for 2002-2008 was reviewed. Patients with PAI were categorized as those who underwent successful SNOM (operative management not required) and those who failed SNOM (surgery required more than 4 h after admission). Yearly rates of SNOM versus non-therapeutic laparotomy (NTL) were plotted. Multivariable regression analysis was performed to identify factors associated with failed SNOM and mortality.
A total of 12 707 patients with abdominal gunshot and 13 030 with stab wounds were identified. Rates of SNOM were 22.2 per cent for gunshot and 33.9 per cent for stab wounds, and increased with time (P < 0.001). There was a strong correlation between the rise in SNOM and the decline in NTL (r = - 0.70). SNOM failed in 20.8 and 15.2 per cent of patients with gunshot and stab wounds respectively. Factors predicting failure included the need for blood transfusion (odds ratio (OR) 1.96, 95 per cent confidence interval 1.11 to 3.46) and a higher injury score. Failed SNOM was independently associated with mortality in both the gunshot (OR 4.48, 2.07 to 9.70) and stab (OR 9.83, 3.44 to 28.00) wound groups.
The practice of SNOM is increasing, with an associated decrease in the rate of NTL for PAI. In most instances SNOM is successful; however, its failure is associated with increased mortality. Careful patient selection and adherence to protocols designed to decrease the failure rate of SNOM are recommended.
本研究旨在探讨穿透性腹部损伤(PAI)选择性非手术治疗(SNOM)的实践趋势,并确定与 SNOM 失败相关的因素。
回顾了 2002 年至 2008 年国家创伤数据库。将 PAI 患者分为成功接受 SNOM(无需手术治疗)和 SNOM 失败(入院后 4 小时以上需要手术)的患者。绘制了每年 SNOM 与非治疗性剖腹术(NTL)的比率。进行多变量回归分析以确定与 SNOM 失败和死亡率相关的因素。
共确定了 12707 例腹部枪击伤和 13030 例刺伤患者。枪击伤的 SNOM 率为 22.2%,刺伤的 SNOM 率为 33.9%,且随时间增加(P<0.001)。SNOM 上升与 NTL 下降之间存在很强的相关性(r=-0.70)。枪击伤和刺伤患者的 SNOM 失败率分别为 20.8%和 15.2%。预测失败的因素包括输血需求(优势比(OR)1.96,95%置信区间 1.11 至 3.46)和更高的损伤评分。SNOM 失败与枪击伤(OR 4.48,2.07 至 9.70)和刺伤(OR 9.83,3.44 至 28.00)两组患者的死亡率独立相关。
SNOM 的应用不断增加,同时 PAI 的 NTL 率也随之下降。在大多数情况下,SNOM 是成功的;然而,其失败与死亡率增加相关。建议仔细选择患者并遵循旨在降低 SNOM 失败率的方案。