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腹腔内感染的发病机制与治疗

Pathogenesis and treatment of intra-abdominal infection.

作者信息

Malangoni M A

机构信息

Department of Surgery, Metro Health Medical Center, Case Western Reserve University, Cleveland, Ohio 14109.

出版信息

Surg Gynecol Obstet. 1990;171 Suppl:31-4.

PMID:2244293
Abstract

Intra-abdominal infection is considered potentially life-threatening. Such infection is frequently secondary to perforated viscera, trauma or inflammatory disease. Simple abscesses may be drained percutaneously with roentgenologic guidance; complex abscesses often require open surgical drainage. Secondary peritonitis is usually polymicrobial; broad-spectrum antimicrobial therapy effective against aerobic and anaerobic gram-negative bacteria, as well as gram-positive organisms, is essential. Newer antibiotics, administered either singly or in combination, have been used successfully to treat intra-abdominal infection while avoiding the toxicity of aminoglycosides.

摘要

腹腔内感染被认为有潜在生命危险。这种感染常继发于内脏穿孔、创伤或炎症性疾病。简单的脓肿可在放射学引导下经皮引流;复杂脓肿通常需要开放手术引流。继发性腹膜炎通常是多种微生物感染;针对需氧和厌氧革兰氏阴性菌以及革兰氏阳性菌有效的广谱抗菌治疗至关重要。单独或联合使用的新型抗生素已成功用于治疗腹腔内感染,同时避免了氨基糖苷类药物的毒性。

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Pathogenesis and treatment of intra-abdominal infection.腹腔内感染的发病机制与治疗
Surg Gynecol Obstet. 1990;171 Suppl:31-4.
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Current concepts in clinical therapeutics: intra-abdominal infections.临床治疗学的当前概念:腹腔内感染
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引用本文的文献

1
The treatment of severe intra-abdominal infections: the role of piperacillin/tazobactam.严重腹腔内感染的治疗:哌拉西林/他唑巴坦的作用
Intensive Care Med. 1994 Jul;20 Suppl 3:S35-8. doi: 10.1007/BF01745249.