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肝脓肿、腹腔内脓肿及盆腔内脓肿的成功抗菌治疗。

Successful antimicrobial therapy of hepatic, intra-abdominal and intrapelvic abscesses.

作者信息

Ralph E D

出版信息

Can Med Assoc J. 1984 Sep 15;131(6):605-7.

PMID:6383589
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1483613/
Abstract

Antimicrobial therapy without surgical drainage or therapeutic aspiration was effective in the management of four patients with deep abscesses ranging in diameter from 1.3 to 10.0 cm. Two of the patients had multiple hepatic abscesses, one had hepatic, intra-abdominal and intrapelvic abscesses, and one had an intrapelvic abscess alone. Anaerobic bacteria were isolated from the blood or abscesses in all four patients, and an aerobic-anaerobic infection was present in one patient. The patients were treated with metronidazole, alone or in combination with other antibiotics, for 3 to 6 weeks. Therefore, in selected patients with deep abscesses, a therapeutic trial of antimicrobial agents instead of surgery may be justified.

摘要

对于4例直径为1.3至10.0厘米的深部脓肿患者,在未进行手术引流或治疗性穿刺抽吸的情况下,抗菌治疗有效。其中2例患者有多个肝脓肿,1例有肝、腹腔内和盆腔内脓肿,1例仅有盆腔内脓肿。所有4例患者的血液或脓肿中均分离出厌氧菌,1例患者存在需氧菌 - 厌氧菌混合感染。患者接受甲硝唑单独或与其他抗生素联合治疗3至6周。因此,对于部分深部脓肿患者,进行抗菌药物的治疗性试验而非手术可能是合理的。

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Central nervous system toxicity associated with metronidazole therapy.与甲硝唑治疗相关的中枢神经系统毒性。
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