Division of Metabolism, Endocrinology and Diabetes, Department of Medicine, University of Michigan Health System, Ann Arbor, MI 48105, USA.
Med Clin North Am. 2012 Mar;96(2):297-310. doi: 10.1016/j.mcna.2012.01.013. Epub 2012 Feb 14.
Thyroid gland dysfunction is prevalent in older adults and may be associated with significant morbidity if misdiagnosed and left untreated. Because of a decreased number of symptoms at presentation, an increased susceptibility to adverse events if not treated, and a greater likelihood of harm from treatment, the diagnosis and management of thyroid disorders in older adults can be challenging. This review focuses on the epidemiology, clinical presentation, risks and complications, and management of thyroid disorders in older adults, including hyperthyroidism, hypothyroidism, thyroid nodules, and thyroid cancer.
甲状腺功能障碍在老年人中较为常见,如果误诊和未经治疗,可能会导致严重的发病。由于老年人的症状减少,不治疗则更易发生不良反应,以及治疗带来的危害更大,因此,老年人甲状腺疾病的诊断和管理具有挑战性。本文重点讨论了老年人甲状腺疾病(包括甲状腺功能亢进症、甲状腺功能减退症、甲状腺结节和甲状腺癌)的流行病学、临床表现、风险和并发症以及管理。