Key Laboratory of Polyoxometalates Science of Ministry of Education, Northeast Normal University, Changchun 130024, PR China.
Anal Chim Acta. 2012 Apr 20;723:39-44. doi: 10.1016/j.aca.2012.02.036. Epub 2012 Feb 25.
Fluorine tin oxide (FTO) electrode modified by copper oxide microfibers (CuO-MFs) composed of numerous interconnected CuO nanoparticles (CuO-NPs) for nonenzymatic glucose sensor was prepared by electrospinning precursor containing high percentage content of copper nitrate with subsequent calcination. The results of scanning electron microscope (SEM) showed the size of CuO particles composing CuO-MFs depended on the percentage content of copper nitrate in precursor solution. With increasing the percentage content of copper nitrate, the interconnected CuO-NPs would gradually replace the large-size CuO particles to accumulate the CuO-MFs, which have the potential to provide larger surface area and more reaction sites for electrocatalytic activity toward glucose. As a glucose sensor, the CuO-MFs modified FTO electrode prepared by 40 wt.% of copper nitrate exhibited a high sensitivity of 2321 μA mM(-1) cm(-2) with a low detection limit of 2.2 nM (signal/noise ratio (S/N)=3). Additionally, the application of the CuO-MFs modified FTO electrode as a glucose sensor for biological samples was demonstrated with satisfactory results.
基于铜（Cu）硝酸盐含量的电纺丝前驱体制备氧化铜（CuO）微纤维（CuO-MFs）修饰的掺氟氧化锡（FTO）电极用于非酶葡萄糖传感器，CuO-MFs 由大量相互连接的 CuO 纳米颗粒（CuO-NPs）组成。扫描电子显微镜（SEM）结果表明，组成 CuO-MFs 的 CuO 颗粒的尺寸取决于前驱体溶液中 Cu （NO3）2 的含量。随着 Cu （NO3）2 含量的增加，相互连接的 CuO-NPs 将逐渐取代大尺寸的 CuO 颗粒来积累 CuO-MFs，这为电催化葡萄糖氧化反应提供了更大的表面积和更多的反应位点。作为葡萄糖传感器，用 40wt.%Cu （NO3）2 制备的 CuO-MFs 修饰的 FTO 电极具有高灵敏度（2321 μA mM-1 cm-2）和低检测限（2.2 nM（信噪比（S/N）=3））。此外，CuO-MFs 修饰的 FTO 电极作为生物样品葡萄糖传感器的应用也取得了令人满意的结果。
