Department of Chemistry, Faculty of Science, University of Jiroft, Jiroft, Iran.
Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Science, Kerman, Iran.
Sci Rep. 2023 May 17;13(1):7999. doi: 10.1038/s41598-023-34569-y.
A practical technique was applied to fabricate CuO nanostructures for use as the electrocatalyst. The green synthesis of cupric oxide nanoparticles (CuO NPs) via co-precipitation is described in this paper using an aqueous extract of Origanum majorana as both reductant and stabilizer, accompanied by characterization via XRD, SEM, and FTIR. The XRD pattern revealed no impurities, whereas SEM revealed low agglomerated spherical particles. CuO nanoparticles and multi wall carbon nanotubes (MWCNTs) have been used to create a modified carbon paste electrode. Voltammetric methods were used to analyze Tramadol using CuONPs/MWCNT as a working electrode. The produced nanocomposite showed high selectivity for Tramadol analysis with peak potentials of ~ 230 mV and ~ 700 mV and Excellent linear calibration curves for Tramadol ranging from 0.08 to 500.0 µM with a correlation coefficient of 0.9997 and detection limits of 0.025. Also, the CuO NPs/MWCNT/CPE sensor shows an an appreciable sensitivity of 0.0773 μA/μM to tramadol. For the first time the B3LYP/LanL2DZ, quantum method was used to compute DFT to determine nanocomposites' connected energy and bandgap energy. Eventually, CuO NPs/CNT was shown to be effective in detecting Tramadol in actual samples, with a recovery rate ranging from 96 to 104.3%.
一种实用的技术被应用于制备氧化铜纳米结构作为电催化剂。本文通过共沉淀法描述了利用牛至的水提物作为还原剂和稳定剂，合成氧化铜纳米粒子（CuO NPs），并通过 XRD、SEM 和 FTIR 进行了表征。XRD 图谱表明没有杂质，而 SEM 则显示出低团聚的球形颗粒。氧化铜纳米粒子和多壁碳纳米管（MWCNTs）已被用于制备修饰碳糊电极。使用 CuONPs/MWCNT 作为工作电极的伏安法分析曲马多。所制备的纳米复合材料对曲马多分析具有高选择性，峰电位约为 230 mV 和 700 mV，以及从 0.08 到 500.0 µM 的 Tramadol 的良好线性校准曲线，相关系数为 0.9997，检测限为 0.025。此外，CuO NPs/MWCNT/CPE 传感器对曲马多的灵敏度为 0.0773 μA/μM。首次使用 B3LYP/LanL2DZ、量子方法进行了 DFT 计算，以确定纳米复合材料的连接能和带隙能。最终，CuO NPs/CNT 被证明在实际样品中检测曲马多有效，回收率在 96%到 104.3%之间。
