Ilagan N B, Elias E G, Liang K C, Kazzi G, Piligian J, Khatib G
Department of Pediatrics, Wayne State University, Grace Hospital, Detroit, Michigan.
Acta Obstet Gynecol Scand. 1990;69(4):287-90. doi: 10.3109/00016349009036148.
In a study of 82 cases of clinical chorioamnionitis in which no antibiotics were administered antenatally, significant villous edema was observed in 51 placentas (62%). Polymorphonuclear leukocyte invasion of the placental plate was found in 53 placentas (65%). The presence of SVE was significantly associated with placental bacterial recovery, occurrence of prolonged rupture of membranes, lower one minute Apgar score, the need for resuscitation and significant neonatal respiratory problems. Findings suggest that bacteria-related placental villous edema can lead to significant perinatal and neonatal morbidities.
在一项针对82例临床绒毛膜羊膜炎且产前未使用抗生素的研究中，51例胎盘（62%）观察到明显的绒毛水肿。53例胎盘（65%）发现胎盘板有中性粒细胞浸润。SVE的存在与胎盘细菌检出、胎膜长时间破裂的发生、1分钟阿氏评分较低、复苏需求及显著的新生儿呼吸问题显著相关。研究结果表明，细菌相关的胎盘绒毛水肿可导致显著的围产期和新生儿发病情况。
