1Department of Animal Biotechnology, University of Nevada-Reno, Mail Stop 202, NV 89557, Reno, USA.
Animal. 2007 Jul;1(6):865-71. doi: 10.1017/S1751731107000018.
Little is known about the relationship between feed intake behaviour and cholesterol levels in humans. This can be attributed to the fact that feed intake behaviour in humans is difficult to assess. The relationships between feed intake, feed efficiency and feed intake behaviour, and cholesterol and triglyceride levels were investigated at an average age of 187 days, in a pig model consisting of 202 Duroc barrows. Feed intake and feed intake behaviour were recorded individually and daily by means of an electronic identification system. Animals with high levels of total cholesterol also had high levels of high-density lipoprotein (HDL), low-density lipoprotein (LDL) cholesterol and triglycerides. Animals with high levels of HDL also had high levels of LDL and triglycerides, and animals with high levels of LDL also had high levels of triglycerides. Animals with higher BW, higher backfat thickness, higher BW gain, higher gain of backfat deposition, higher feed intake, higher residual feed intake (RFI) and higher feed intake rate had higher levels of total, HDL and LDL plasma cholesterol. Results indicate that the relationship between feed intake and cholesterol levels is a long-term relationship, while the relationship between RFI and cholesterol levels is more of a short-term nature. The relationship between intake rate and cholesterol plasma levels disappeared after correction for the amount of feed consumed. Results indicate that feed intake independent of metabolic BW, growth and fatness, i.e. 'RFI', was positively correlated with cholesterol plasma levels. This suggests that eating food over and above the maintenance and growth requirements constitutes a health risk independent of the level of fatness.
人们对人类的采食量行为与胆固醇水平之间的关系知之甚少。这可以归因于这样一个事实，即人类的采食量行为很难评估。在一个由 202 头杜洛克公猪组成的猪模型中，在平均年龄为 187 天时，研究了采食量、饲料效率和采食量行为与胆固醇和甘油三酯水平之间的关系。通过电子识别系统对动物进行个体和每日的采食量和采食量行为记录。总胆固醇水平高的动物也具有高水平的高密度脂蛋白（HDL）、低密度脂蛋白（LDL）胆固醇和甘油三酯。HDL 水平高的动物也具有高水平的 LDL 和甘油三酯，而 LDL 水平高的动物也具有高水平的甘油三酯。BW 较高、背脂较厚、BW 增重较高、背脂沉积增重较高、采食量较高、残余采食量（RFI）较高和采食量较高的动物具有较高的总胆固醇、HDL 和 LDL 血浆胆固醇水平。结果表明，采食量与胆固醇水平之间的关系是一种长期关系，而 RFI 与胆固醇水平之间的关系则更具有短期性质。在校正消耗的饲料量后，摄入率与胆固醇血浆水平之间的关系消失了。结果表明，与代谢 BW、生长和肥胖无关的采食量，即“RFI”，与胆固醇血浆水平呈正相关。这表明，摄入超过维持和生长所需的食物会构成独立于肥胖程度的健康风险。
