Tofler O B, Tofler G H
Cardiology Department, Royal Perth Hospital, Western Australia.
Am J Cardiol. 1990 Dec 1;66(19):1355-8. doi: 10.1016/0002-9149(90)91167-5.
Mitral systolic clicks and murmurs together with associated symptoms constitute a major reason for cardiologic referral. Although echocardiography with Doppler study enables characterization of the mitral valve apparatus and quantification of regurgitation, its use has resulted in an overemphasis of the technical diagnosis of mitral valve prolapse and an undervaluation of diagnosis based on physical examination. To determine the clinical significance of an auscultatory classification of mitral systolic clicks with or without precordial systolic murmurs, 1 consultant's medical records of 291 patients with these signs were reviewed. Based on initial auscultatory findings, patients were divided into: (1) single or multiple apical systolic clicks with no murmur (n = 99); (2) single or multiple apical systolic clicks and a late systolic murmur (n = 129); and (3) single or multiple apical clicks and an apical pansystolic murmur or murmur beginning in the first half of systole (n = 63). The average duration of patient follow-up was 8 years (range 1 to 30). The prognosis was excellent for patients from all 3 classes. Two cardiac-related deaths occurred: 1 each from classes 1 and 2. Mitral valve surgery was performed in 3 class 2 patients (2%) and in 2 class 3 patients (3%). No patients developed endocarditis during follow-up. Palpitations, with varying anxiety overlay, constituted a major indication for cardiologic referral in all 3 classes. Auscultatory findings were valuable to the physician for explanation and relief of patient anxiety. For patient management, use of an auscultatory classification may be preferable to the technically generated term "mitral valve prolapse."
二尖瓣收缩期喀喇音和杂音以及相关症状是心脏科转诊的主要原因。尽管超声心动图结合多普勒研究能够对二尖瓣装置进行特征描述并对反流进行量化,但它的使用导致了对二尖瓣脱垂技术诊断的过度强调,而对基于体格检查的诊断重视不足。为了确定伴有或不伴有心前区收缩期杂音的二尖瓣收缩期喀喇音听诊分类的临床意义,回顾了1位会诊医生记录的291例有这些体征患者的病历。根据最初的听诊结果,患者被分为:(1)单个或多个心尖收缩期喀喇音且无杂音(n = 99);(2)单个或多个心尖收缩期喀喇音和晚期收缩期杂音(n = 129);(3)单个或多个心尖喀喇音和心尖全收缩期杂音或始于收缩期前半段的杂音(n = 63)。患者的平均随访时间为8年(范围1至30年)。所有3组患者的预后都很好。发生了2例与心脏相关的死亡:第1组和第2组各1例。2例2组患者(2%)和2例3组患者(3%)接受了二尖瓣手术。随访期间没有患者发生心内膜炎。心悸伴不同程度的焦虑是所有3组患者心脏科转诊的主要指征。听诊结果对医生解释和缓解患者焦虑很有价值。对于患者管理,使用听诊分类可能比技术上产生的术语“二尖瓣脱垂”更可取。