Gaze R M, Wilson M A, Taylor J S
Department of Zoology, University of Edinburgh, United Kingdom.
Anat Embryol (Berl). 1990;182(2):181-94. doi: 10.1007/BF00174017.
The path through the chiasma followed by regenerating optic nerve fibres in Xenopus tadpoles was studied at light- and electron-microscopic levels, and with horseradish peroxidase as a fibre label. Over the period (5-10 days) in which regenerating fibres reach and cross the chiasma, they did not follow residual deep fibres through the chiasma, nor were they associated with the trail of degeneration in the chiasma which represented the remains of the deeper (older) parts of the original projection. The regenerating optic fibres were always seen in close association with the inner surfaces of the ependymoglial endfeet, or in the extracellular spaces that lie close to the endfeet in the most superficial part of the chiasma, where newly-growing fibres from the retinal margin are normally to be found.
利用辣根过氧化物酶作为纤维标记物，在光学显微镜和电子显微镜水平上，研究了非洲爪蟾蝌蚪视神经纤维再生时通过视交叉的路径。在再生纤维到达并穿过视交叉的这段时间（5 - 10天）内，它们并未跟随残留的深层纤维穿过视交叉，也未与视交叉中的变性痕迹相关联，而视交叉中的变性痕迹代表了原始投射较深（较老）部分的残余。再生的视神经纤维总是紧密地与室管膜神经胶质终足的内表面相关联，或者存在于视交叉最表层靠近终足的细胞外间隙中，而视网膜边缘新生长的纤维通常就在此处。
