Taylor J S, Gaze R M
Department of Zoology, University of Edinburgh, United Kingdom.
Anat Embryol (Berl). 1990;181(4):405-12. doi: 10.1007/BF00186913.
There is evidence, from a variety of species, that axons arising from the two eyes interact as they pass through the optic chiasma. In this paper we examine the effect of altering the composition of the normal chiasmatic environment on the course taken by regenerating axons in Xenopus. We show that the usual contralateral route of such axons in the optic chiasma is not affected by the absence of axons from the other eye. We have not observed any influence of embryonic enucleation, or eye removal before the onset of metamorphosis, on either the normal ipsilaterally projecting axons or the contralateral route taken by regenerating axons. Further, we have found no effect of the degeneration of the other projection, either for long or short periods of time, suggesting that axonal debris does not influence the course of regenerating axons. The simultaneous regeneration of the two projections also has no effect on the trajectory of regenerating axons. We conclude that in spite of the close association of axons from the two eyes in the chiasma, there is no interaction involved in Xenopus in the generation of the decussation pattern.
从多种物种的研究中有证据表明，来自双眼的轴突在穿过视交叉时会相互作用。在本文中，我们研究了改变正常视交叉环境的组成对非洲爪蟾再生轴突所走路径的影响。我们发现，视交叉中此类轴突通常的对侧路径不受另一只眼轴突缺失的影响。我们没有观察到胚胎期摘除眼球或在变态发育开始前摘除眼球，对正常同侧投射轴突或再生轴突所走的对侧路径有任何影响。此外，我们发现另一个投射的退化，无论时间长短，都没有影响，这表明轴突碎片不会影响再生轴突的路径。两个投射同时再生对再生轴突的轨迹也没有影响。我们得出结论，尽管视交叉中来自双眼的轴突联系紧密，但在非洲爪蟾中，交叉模式的形成过程中不存在相互作用。
