Collet L, Moulin A, Gartner M, Morgon A
Laboratoire d'Explorations Fonctionnelles Neurosensorielles, Hôpital Edouard Herriot, Lyon, France.
Ann Otol Rhinol Laryngol. 1990 Dec;99(12):993-7. doi: 10.1177/000348949009901212.
Outer hair cells of the organ of Corti play an important part in the genesis of evoked otoacoustic emissions (EOAEs), which are related to cochlear biomechanics. The aim of this study was to investigate the age factor in relation to EOAEs in 166 ears of subjects between 6 weeks and 83 years of age. The results show that when age increases, the presence of EOAEs by age group and the frequency peak in spectral analysis decrease, and EOAE threshold increases. Thus, there is an effect of age upon EOAEs, and it seems linked with alteration of cochlear biomechanics and/or hair cell loss. Such an effect has to be taken into consideration when EOAEs are used in clinical applications, and limits the use of EOAEs in older subjects.
柯蒂氏器的外毛细胞在诱发耳声发射（EOAE）的产生中起着重要作用，耳声发射与耳蜗生物力学有关。本研究的目的是调查6周龄至83岁受试者166只耳中与耳声发射相关的年龄因素。结果显示，随着年龄增长，按年龄组划分的耳声发射出现率及频谱分析中的频率峰值降低，且耳声发射阈值升高。因此，年龄对耳声发射有影响，这似乎与耳蜗生物力学改变和/或毛细胞损失有关。在临床应用中使用耳声发射时必须考虑到这种影响，这限制了耳声发射在老年受试者中的应用。
