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小儿活体肝移植术中门静脉低流量的处理。

Intra-operative management of low portal vein flow in pediatric living donor liver transplantation.

机构信息

Liver Transplantation Program, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.

出版信息

Transpl Int. 2012 May;25(5):586-91. doi: 10.1111/j.1432-2277.2012.01464.x. Epub 2012 Mar 26.

DOI:10.1111/j.1432-2277.2012.01464.x
PMID:22448749
Abstract

For pediatric living donor liver transplantation, portal vein complications cause significant morbidity and graft failure. Routine intra-operative Doppler ultrasound is performed after graft reperfusion to evaluate the flow of portal vein. This retrospective study reviewed 65 children who had undergone living donor liver transplantation. Seven patients were detected with suboptimal portal vein flow velocity following vascular reconstruction and abdominal closure. They underwent immediate on-table interventions to improve the portal vein flow. Both surgical and endovascular modalities were employed, namely, graft re-positioning, collateral shunt ligation, thrombectomy, revision of anastomosis, inferior mesenteric vein cannulation, and endovascular stenting. The ultrasonographic follow-up assessment for all seven patients demonstrated patent portal vein and satisfactory flow. We reviewed our experience on the different modalities and proposed an approach for our future intra-operative management to improve portal vein flow at the time of liver transplantation.

摘要

对于儿科活体供肝移植,门静脉并发症会导致严重的发病率和移植物失功。在进行再灌注后,通常会在术中进行多普勒超声检查,以评估门静脉的血流情况。本回顾性研究纳入了 65 例行活体供肝移植的儿童患者。7 例患者在血管重建和腹部关闭后发现门静脉血流速度不理想。他们立即接受了术中干预措施以改善门静脉血流。使用了手术和血管内两种方式,包括肝移植、侧支分流结扎、血栓切除术、吻合口修正、肠系膜下静脉插管和血管内支架置入。对所有 7 例患者的超声随访评估显示门静脉通畅,血流满意。我们回顾了不同方式的经验,并提出了我们未来术中管理的方法,以改善肝移植时门静脉血流。

相似文献

1
Intra-operative management of low portal vein flow in pediatric living donor liver transplantation.小儿活体肝移植术中门静脉低流量的处理。
Transpl Int. 2012 May;25(5):586-91. doi: 10.1111/j.1432-2277.2012.01464.x. Epub 2012 Mar 26.
2
Risk factors for intraoperative portal vein thrombosis in pediatric living donor liver transplantation.小儿活体肝移植术中门静脉血栓形成的危险因素
Clin Transplant. 2004 Aug;18(4):390-4. doi: 10.1111/j.1399-0012.2004.00178.x.
3
Section 6. Management of extensive nontumorous portal vein thrombosis in adult living donor liver transplantation.第六节:成人活体肝移植中广泛非肿瘤性门静脉血栓的处理。
Transplantation. 2014 Apr 27;97 Suppl 8:S23-30. doi: 10.1097/01.tp.0000446270.20934.05.
4
Intraoperative Doppler ultrasound in liver transplantation.肝移植术中的多普勒超声检查
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6
Using low graft/recipient's body weight ratio graft with portal flow modulation an effective way to prevent small-for-size syndrome in living-donor liver transplant: a retrospective analysis.采用低移植物/受者体重比的移植物并调节门静脉血流是预防活体肝移植中小体积肝综合征的有效方法:一项回顾性分析。
Exp Clin Transplant. 2014 Oct;12(5):437-42.
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The inferior mesenteric vein to the left gonadal vein shunt for gastroesophageal varices and extrahepatic portal vein thrombosis after living donor liver transplantation: a case report.活体肝移植后肠系膜下静脉至左性腺静脉分流术治疗胃食管静脉曲张和肝外门静脉血栓形成:1例报告
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Vascular complications in living related liver transplantation detected with intraoperative and postoperative Doppler US.通过术中及术后多普勒超声检测活体亲属肝移植中的血管并发症。
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Role of Doppler Ultrasonography in Defining Normal and Abnormal Graft Hemodynamics After Living-Donor Liver Transplant.多普勒超声检查在活体供肝移植后明确移植肝正常与异常血流动力学中的作用
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Intraoperative stent placement for the treatment of acute portal vein complications in pediatric living donor liver transplantation.术中放置支架治疗小儿活体肝移植急性门静脉并发症
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引用本文的文献

1
Intraoperative Doppler sonogram in pediatric liver transplants: a pictorial review of intraoperative and early postoperative complications.小儿肝移植术中多普勒超声检查:术中及术后早期并发症的影像学综述
Pediatr Radiol. 2018 Mar;48(3):401-410. doi: 10.1007/s00247-017-4053-0. Epub 2017 Dec 22.
2
Doppler ultrasonography in living donor liver transplantation recipients: Intra- and post-operative vascular complications.活体供肝移植受者的多普勒超声检查:术中和术后血管并发症
World J Gastroenterol. 2016 Jul 21;22(27):6145-72. doi: 10.3748/wjg.v22.i27.6145.
3
Living donor liver transplantation with body-weight more or less than 10 kilograms.
活体供肝肝移植,供体体重与受体相差10千克左右。
World J Gastroenterol. 2015 Jun 21;21(23):7248-53. doi: 10.3748/wjg.v21.i23.7248.