Wahyudi Edy R, Setiati Siti, Harimurti Kuntjoro, Dewiasty Esthika, Istanti Rahmi
Department of Internal Medicine, University of Indonesia, Jakarta, Indonesia.
Acta Med Indones. 2012 Jan;44(1):47-52.
to determine risk factors for depressive symptom changes in geriatric outpatients.
a prospective cohort study was conducted on 106 geriatric outpatients at Integrated Geriatric Clinic Cipto Mangunkusumo Hospital, Jakarta in 2010. A structured questionnaire was applied to obtain independent variable such as age, sex, educational level, chronic diseases (diabetes mellitus, chronic kidney diseases, hypertension, dyslipidemia, and osteoarthritis), functional status (WHO-Unescap score), nutritional status (body mass index), health related quality of life (Eq5D score), hospitalization within 6 months, and total calorie intake. Depressive symptom as dependent variable was assessed using Geriatric Depression Scale. The association between aforementioned various factors with depressive symptom changes were analyzed using multiple logistic regression analysis.
most of subjects were women (63.2%), aged 70 years old and older (71.0%) and had hypertension (82.1%). There were 22.6% subjects with increase in GDS score during 6-month follow-up. Bivariable analysis showed that diabetes mellitus and chronic kidney diseases were significantly associated with depressive symptom changes. Multiple logistic regression showed that variable which independently associated with depressive symptom changes was uncontrolled chronic kidney disease (OR 3.390; 95% CI 1.07-10.76.
uncontrolled chronic kidney disease is risk factor for depressive symptom changes in geriatric outpatients.
确定老年门诊患者抑郁症状变化的风险因素。
2010年在雅加达芝多·曼古库苏莫医院综合老年病诊所对106名老年门诊患者进行了一项前瞻性队列研究。应用结构化问卷获取年龄、性别、教育程度、慢性疾病(糖尿病、慢性肾病、高血压、血脂异常和骨关节炎)、功能状态(世界卫生组织-联合国亚太经社会评分)、营养状况(体重指数)、健康相关生活质量(欧洲五维度健康量表评分)、6个月内住院情况以及总热量摄入等自变量。使用老年抑郁量表评估作为因变量的抑郁症状。采用多元逻辑回归分析上述各种因素与抑郁症状变化之间的关联。
大多数受试者为女性(63.2%),年龄在70岁及以上(71.0%),患有高血压(82.1%)。在6个月的随访期间,22.6%的受试者老年抑郁量表评分增加。双变量分析表明,糖尿病和慢性肾病与抑郁症状变化显著相关。多元逻辑回归显示,与抑郁症状变化独立相关的变量是未得到控制的慢性肾病(比值比3.390;95%置信区间1.07 - 10.76)。
未得到控制的慢性肾病是老年门诊患者抑郁症状变化的风险因素。