Department of Gastroenterology, Hepatology and Endocrinology, Charité Universitätsmedizin Berlin, Charitéplatz 1, Berlin, Germany.
Br J Nutr. 2009 Dec;102(11):1663-7. doi: 10.1017/S0007114509990900. Epub 2009 Jul 22.
Malnutrition and depression are highly prevalent in the institutionalised elderly and can lead to unfavourable outcomes. The aim of the present study was to assess associations between nutritional status and depressive symptoms and to explore their impact on self-caring capacity and quality of life (QoL) in elderly nursing-home residents (NHR). We conducted a cross-sectional study with 114 NHR (eighty-six female) with a mean age of 84.6 (sd 9.1) years. Nutritional status was assessed with the Mini Nutritional Assessment (MNA). Depressive symptoms were rated with the Geriatric Depression Scale (GDS). Self-caring capacity was measured with the Barthel index (BI) and QoL was assessed with the short-form thirty-six-item (SF-36) questionnaire. Of the NHR, twenty-six (22.8 %) were malnourished according to the MNA and sixty-six (57.9 %) were at nutritional risk. Of the residents, seventy-five could be assessed with the GDS, whereof sixteen (21.3 %) had major and twenty-six (34.7 %) had minor depressive symptoms. GDS scores tended to be higher in patients with impaired nutritional status (5.4 (sd 3.6) in well-nourished subjects and 6.9 (sd 3.2) in residents with malnutrition or at risk of malnutrition). The MNA correlated significantly with the GDS (r - 0.313; P = 0.006) and the GDS emerged as the only independent risk factor for malnutrition in a multiple regression analysis, whereas age, sex, care level, number of prescriptions and self-caring capacity had no influence. The BI was not reduced in patients with a high GDS. QoL was affected in malnourished residents as well as in study participants with depressive symptoms. The results of the present study point towards an association between malnutrition and depressive symptoms. However, the relationship is complex and it remains unclear whether depression in NHR is the cause or consequence of impaired nutritional status. Further studies are needed to identify the direction of this relationship and to assess the effect of depression treatment on nutritional and functional status as well as on QoL.
营养不良和抑郁在机构化老年人中非常普遍,可能导致不良后果。本研究的目的是评估营养状况与抑郁症状之间的关联,并探讨它们对老年疗养院居民(NHR)自我护理能力和生活质量(QoL)的影响。我们进行了一项横断面研究,纳入了 114 名 NHR(86 名女性),平均年龄为 84.6(标准差 9.1)岁。营养状况采用 Mini Nutritional Assessment(MNA)评估。抑郁症状采用老年抑郁量表(GDS)评估。自我护理能力采用巴氏指数(BI)测量,生活质量采用 36 项简短健康状况调查问卷(SF-36)评估。根据 MNA,114 名 NHR 中有 26 名(22.8%)存在营养不良,66 名(57.9%)存在营养风险。在可评估 GDS 的 75 名居民中,16 名(21.3%)存在严重抑郁症状,26 名(34.7%)存在轻度抑郁症状。营养状况受损的患者 GDS 评分较高(营养良好者为 5.4(标准差 3.6),营养不良或存在营养不良风险者为 6.9(标准差 3.2))。MNA 与 GDS 显著相关(r=-0.313,P=0.006),GDS 是多元回归分析中营养不良的唯一独立危险因素,而年龄、性别、护理级别、用药数量和自我护理能力无影响。GDS 高的患者 BI 没有降低。营养不良的居民和有抑郁症状的研究参与者的生活质量都受到影响。本研究结果表明,营养不良与抑郁症状之间存在关联。然而,这种关系很复杂,尚不清楚 NHR 中的抑郁是营养状况受损的原因还是结果。需要进一步的研究来确定这种关系的方向,并评估抑郁治疗对营养和功能状态以及生活质量的影响。