Setiati Siti, Harimurti Kuntjoro, Dewiasty Esthika, Istanti Rahmi
Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia.
Acta Med Indones. 2011 Oct;43(4):237-42.
to determine factors that independently predict health-related quality of life of Indonesian community-dwelling elderly and to obtain scoring system to predict their quality of life.
this is a cross-sectional study covering a sample representative of the Indonesian community-dwelling elderly. The study was conducted among 487 elderly in 43 cities in Indonesia between November-December 2010. A structured questionnaire was applied to obtain independent variable such as age, sex, number of diseases, present activities, functional status (ADL score), cognitive status (AMT score), nutritional status (NRI score), and depression status. Quality of life as dependent variable was assessed by Euroqol-5D (Eq-5D). We defined good quality of life as 3 or more dimensions of Eq5D having score of 1. Predictors of quality of life were identified using multiple logistic regression analysis. We constructed a scoring system based on coefficients in multivariable analysis. Calibration performance of the score was evaluated by Hosmer-Lemeshow tests while discrimination performance was evaluated with the c-statistic.
most of the subjects were male (52.2%) and aged between 60-70 years old (75.8%). Prevalence of poor quality of life in this study was 14.9%. Bivariable analysis showed that all independent variables were significantly associated with quality of life. Multiple logistic regression analysis showed that factors predicting poor quality of life were female (OR 1.9; 95% CI 1.0-3.6), poor nutritional status (OR 2.7; 95% CI (1.2-0.8), having >2 chronic diseases (OR 3.6; 95% CI 1.9-6.8), low functional status (OR 4.2; 95% CI 2.2-8.2), and depression (OR 6.3; 95% CI 3.3-12.1). Performance of the risk score revealed Hosmer Lemeshow test p=0.86 and c-statistic 0.87 (95% CI 0.83-0.92).
the following factors were identified as predictive factors of HRQoL in Indonesian community-dwelling elderly: sex, nutritional status, number of chronic diseases, functional status, and depression status. The risk score developed based on those predictors showed good performance to accurately predict poor quality of life.
确定能独立预测印度尼西亚社区居住老年人健康相关生活质量的因素,并获得预测其生活质量的评分系统。
这是一项横断面研究,涵盖了具有印度尼西亚社区居住老年人代表性的样本。该研究于2010年11月至12月在印度尼西亚43个城市的487名老年人中进行。应用结构化问卷获取年龄、性别、疾病数量、当前活动、功能状态(日常生活活动能力评分)、认知状态(简易精神状态检查表评分)、营养状态(营养风险指数评分)和抑郁状态等自变量。将欧洲五维健康量表(Eq-5D)评估的生活质量作为因变量。我们将Eq5D中3个或更多维度得分为1定义为良好生活质量。使用多元逻辑回归分析确定生活质量的预测因素。我们基于多变量分析中的系数构建了一个评分系统。通过Hosmer-Lemeshow检验评估评分的校准性能,同时用c统计量评估区分性能。
大多数受试者为男性(52.2%),年龄在60 - 70岁之间(75.8%)。本研究中生活质量差的患病率为14.9%。双变量分析表明,所有自变量均与生活质量显著相关。多元逻辑回归分析表明,预测生活质量差的因素为女性(比值比1.9;95%置信区间1.0 - 3.6)、营养状况差(比值比2.7;95%置信区间1.2 - 0.8)、患有>2种慢性病(比值比3.6;95%置信区间1.9 - 6.8)、功能状态低(比值比4.2;95%置信区间2.2 - 8.2)和抑郁(比值比6.3;95%置信区间3.3 - 12.1)。风险评分的性能显示Hosmer Lemeshow检验p = 0.86,c统计量为0.87(95%置信区间0.83 - 0.92)。
以下因素被确定为印度尼西亚社区居住老年人健康相关生活质量的预测因素:性别、营养状况、慢性病数量、功能状态和抑郁状态。基于这些预测因素开发的风险评分在准确预测生活质量差方面表现良好。