Endocrine. 2012 Jun;41(3):350-2. doi: 10.1007/s12020-012-9657-4. Epub 2012 Mar 27.
For more than 200 years initially seen as a cause of gout, speaking in a politically correct 21st century term, a disease of the rich and very well nourished people, many experimental and epidemiological studies have associated increased levels of serum uric acid (UA) with the classical components of the metabolic syndrome (MS), type 2 diabetes, and cardiovascular disease [1]. This association with components of the MS is seen even in children and adolescents [2]. The topic of increased UA concentrations, its consequences or associations is getting more important nowadays due to the increments in the prevalence of obesity and the MS in both developed and developing countries.
两百多年来，尿酸（UA）最初被视为痛风的病因，用 21 世纪政治正确的术语来说，这是一种富贵病，与营养状况良好的人群相关。许多实验和流行病学研究表明，血清 UA 水平升高与代谢综合征（MS）的经典成分、2 型糖尿病和心血管疾病相关[1]。即使在儿童和青少年中也能观察到这种与 MS 成分的关联[2]。由于肥胖和 MS 在发达国家和发展中国家的患病率不断增加，UA 浓度升高、其后果或关联的问题变得更加重要。
