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主张父母有义务使用胚胎植入前遗传学诊断来获得医疗益处。

The case for a parental duty to use preimplantation genetic diagnosis for medical benefit.

机构信息

Brody School of Medicine, Bioethics and Interdisciplinary Studies, Greenville, NC 27834, USA.

出版信息

Am J Bioeth. 2012;12(4):3-11. doi: 10.1080/15265161.2012.656798.

DOI:10.1080/15265161.2012.656798
PMID:22452463
Abstract

This article explores the possibility that there is a parental duty to use preimplantation genetic diagnosis (PGD) for the medical benefit of future children. Using one genetic disorder as a paradigmatic example, we find that such a duty can be supported in some situations on both ethical and legal grounds. Our analysis shows that an ethical case in favor of this position can be made when potential parents are aware that a possible future child is at substantial risk of inheriting a serious genetic condition. We further argue that a legal case for a duty to use PGD for medical benefit can be made in situations in which potential parents have chosen to conceive through in vitro fertilization and know that any children conceived are at substantial risk of having a serious genetic condition.

摘要

本文探讨了父母是否有义务利用胚胎植入前遗传学诊断(PGD)来保障未来孩子的医疗利益。本文以一种遗传疾病为例,发现基于伦理和法律的理由,在某些情况下这种义务是可以成立的。我们的分析表明,当准父母意识到可能的未来孩子有很大的风险遗传严重的遗传疾病时,支持这种立场在伦理上是合理的。我们进一步认为,在准父母选择通过体外受精受孕且知道所孕育的任何孩子都有很大的风险患有严重遗传疾病的情况下,可以为利用 PGD 进行医疗获益的义务提出法律依据。

相似文献

1
The case for a parental duty to use preimplantation genetic diagnosis for medical benefit.主张父母有义务使用胚胎植入前遗传学诊断来获得医疗益处。
Am J Bioeth. 2012;12(4):3-11. doi: 10.1080/15265161.2012.656798.
2
A parental duty to use PGD: more than we bargained for?
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引用本文的文献

1
Preimplantation Genetic Testing (PGT) to Reduce the Risk for GBA-Related Parkinson's Disease: Expanding the Applications for Embryo Selection.植入前基因检测(PGT)以降低与GBA相关帕金森病的风险:扩大胚胎选择的应用范围
Int J Mol Sci. 2025 Jan 22;26(3):912. doi: 10.3390/ijms26030912.
2
Defining ethical criteria to guide the expanded use of Noninvasive Prenatal Screening (NIPS): Lessons about severity from preimplantation genetic testing.定义指导无创产前筛查(NIPS)扩大应用的伦理标准:来自植入前基因检测的严重性教训。
Eur J Hum Genet. 2025 Mar;33(2):167-175. doi: 10.1038/s41431-024-01714-8. Epub 2024 Oct 26.
3
Subsidizing PGD: The Moral Case for Funding Genetic Selection.
补贴 PGD:为基因选择提供资金的道德理由。
J Bioeth Inq. 2019 Sep;16(3):405-414. doi: 10.1007/s11673-019-09932-2. Epub 2019 Aug 15.
4
Preimplantation genetic diagnosis for inherited neurological disorders.植入前遗传学诊断遗传性神经疾病。
Nat Rev Neurol. 2014 Jul;10(7):417-24. doi: 10.1038/nrneurol.2014.84. Epub 2014 May 27.