Williams K M, Iacono W G, Remick R A, Greenwood P
Department of Psychology, University of British Columbia, Vancouver, Canada.
Br J Psychiatry. 1990 Sep;157:366-72. doi: 10.1192/bjp.157.3.366.
Verbal and visuospatial memory and dichotic listening performance were examined in 15 acutely depressed patients with no history of ECT, 17 depressed patients currently in remission, 15 remitted depressed patients who had received ECT six months or more in the past, and 20 normal controls. The neuropsychological functioning of an additional group of 10 acutely depressed patients was also studied before and two weeks after ECT. The results revealed some evidence of logical and autobiographical memory impairment two weeks following ECT, but no evidence that ECT impaired dichotic listening ability. Rather, a normalisation of hemispheric laterality was apparent on the dichotic listening task following ECT and the concomitant relief from depression. There was also no evidence of cognitive dysfunction on any task in individuals who were tested six months or more following their last ECT treatment.
对15名无ECT治疗史的急性抑郁症患者、17名目前处于缓解期的抑郁症患者、15名过去6个月或更长时间前接受过ECT治疗的缓解期抑郁症患者以及20名正常对照者进行了言语和视觉空间记忆以及双耳分听表现的检查。还对另外一组10名急性抑郁症患者在ECT治疗前和治疗后两周的神经心理功能进行了研究。结果显示，ECT治疗两周后有一些逻辑和自传体记忆受损的证据，但没有证据表明ECT会损害双耳分听能力。相反，ECT治疗后在双耳分听任务中半球偏侧性正常化明显，同时抑郁症症状缓解。在最后一次ECT治疗后6个月或更长时间接受测试的个体中，也没有证据表明在任何任务上存在认知功能障碍。
