Anolik Rachel B, Elenitsas Rosalie, Minakawa Satoko, Nguyen Jennifer, Rubin Adam I
Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104-6142, USA.
Am J Dermatopathol. 2012 Jun;34(4):412-5. doi: 10.1097/DAD.0b013e3182377005.
Nail cosmetics and adornments are widely used in today's society. However, their histologic features are not well characterized. Routine histologic examination and polarization of nail plate specimens in our academic dermatopathology practice at the Hospital of the University of Pennsylvania revealed 3 distinct histologic patterns of nail cosmetics: a hyperpigmented pattern with diffuse fine granular material, a layered pattern with a single linear band of polarizable material, and a hyperpigmented pattern with larger granules containing flecks of polarizable material. In our experience, submitting clinicians rarely indicate the patient's use of nail polish or other enhancements. Recognition of the histologic features of nail cosmetics is important to prevent confusion with dermatoses affecting the nail unit, and it will help dermatopathologists render more accurate diagnoses.
指甲化妆品和装饰品在当今社会广泛使用。然而，它们的组织学特征尚未得到充分描述。在宾夕法尼亚大学医院我们的学术皮肤病理学实践中，对甲板标本进行常规组织学检查和偏振检查发现了指甲化妆品3种不同的组织学模式：一种是伴有弥漫性细颗粒物质的色素沉着模式，一种是伴有一条可偏振物质线性带的分层模式，还有一种是伴有含可偏振物质斑点的较大颗粒的色素沉着模式。根据我们的经验，送检的临床医生很少表明患者使用指甲油或其他美甲产品。认识指甲化妆品的组织学特征对于防止与影响甲单位的皮肤病相混淆很重要，这将有助于皮肤病理学家做出更准确的诊断。
