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采用颊黏膜镶嵌移植修复后尿道复发狭窄。

Inlay buccal mucosal graft for reoperative posterior urethroplasty.

机构信息

Urology, Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan.

出版信息

Kaohsiung J Med Sci. 2012 Apr;28(4):220-4. doi: 10.1016/j.kjms.2011.10.024. Epub 2012 Feb 12.

DOI:10.1016/j.kjms.2011.10.024
PMID:22453071
Abstract

Posterior urethral distraction injury following major pelvic trauma is a surgical challenge. Although rarely seen, cases of failure after formal urethral reconstruction are even more problematic. We adapted the concept of augmented free buccal mucosal grafts, which have been successful in anterior urethroplasty, for repairing the posterior urethra in these rare cases with the aim of reducing the likelihood of penile chordee postoperatively. During 2007-2009, four patients were candidates for the proposed procedure because they had received formal transperineal urethral reconstruction but were unable to urinate through the urethra. The urethra was approached transperineally and opened in the midline, rather than divided. Buccal mucosal grafts of an appropriate size were placed in the created urethral groove from 4- to 8 o'clock in the lithotomy view. After the procedure, the urethral catheter was kept for 3 weeks. All patients voided through the urethra after the procedure. The maximal postoperative urinary flow rates were between 12-15 ml/seconds in all cases for a follow-up period of 18-30 months. The recurrence rate was 50% (2/4). Recurrent strictures were minor, and they showed a web-like stricture ring near the suture line. Restricture within 6 months of surgery responded well to endoscopic internal urethrotomy plus dilatations. In conclusion, without further compromising urethral length, reoperative posterior urethroplasty with the inlay grafting technique can be considered in selective cases.

摘要

后尿道牵引损伤是骨盆创伤后的一种手术挑战。虽然很少见,但正式尿道重建后失败的病例更为棘手。我们借鉴了前尿道成形术中成功应用的带蒂颊黏膜游离移植的概念,将其用于修复这些罕见的后尿道损伤,目的是降低术后发生阴茎下弯的可能性。2007 年至 2009 年间,有 4 名患者适合接受该手术,因为他们已经接受了正式的经会阴尿道重建,但无法通过尿道排尿。经会阴入路,在会阴部中线切开,而不是切开尿道。在膀胱截石位上,从 4 点到 8 点在创建的尿道槽中放置大小合适的颊黏膜移植物。术后留置导尿管 3 周。所有患者术后均通过尿道排尿。术后最大尿流率在 12-15ml/秒之间,随访时间为 18-30 个月。复发率为 50%(2/4)。复发的狭窄是轻微的,在缝线附近显示出网状狭窄环。术后 6 个月内再次出现狭窄的患者,经尿道内切开术加扩张治疗效果良好。总之,在不进一步影响尿道长度的情况下,可考虑对选择的病例采用带蒂镶嵌式移植技术进行再次后尿道成形术。

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Redo-urethroplasty for the management of recurrent urethral strictures in males: a systematic review.男性复发性尿道狭窄的尿道重建术治疗:系统评价。

本文引用的文献

1
A systematic review of graft augmentation urethroplasty techniques for the treatment of anterior urethral strictures.系统评价用于治疗前尿道狭窄的移植物增强尿道成形术技术。
Eur Urol. 2011 May;59(5):797-814. doi: 10.1016/j.eururo.2011.02.010. Epub 2011 Feb 24.
2
Dorsal onlay versus ventral onlay urethroplasty for anterior urethral stricture: a meta-analysis.背侧覆盖术与腹侧覆盖术治疗前尿道狭窄的Meta分析
Urol Int. 2009;83(3):342-8. doi: 10.1159/000241680. Epub 2009 Oct 13.
3
Does a previous end-to-end urethroplasty alter the results of redo end-to-end urethroplasty in patients with traumatic posterior urethral strictures?
World J Urol. 2019 Sep;37(9):1801-1815. doi: 10.1007/s00345-019-02709-7. Epub 2019 Mar 15.
既往端端尿道成形术是否会改变创伤性后尿道狭窄患者再次端端尿道成形术的结果?
Int J Urol. 2008 Oct;15(10):885-8. doi: 10.1111/j.1442-2042.2008.02135.x. Epub 2008 Aug 20.
4
Surgical techniques in substitution urethroplasty using buccal mucosa for the treatment of anterior urethral strictures.使用颊黏膜替代尿道成形术治疗前尿道狭窄的手术技术。
Eur Urol. 2008 Jun;53(6):1162-71. doi: 10.1016/j.eururo.2007.10.011.
5
Bulbar urethroplasty using buccal mucosa grafts placed on the ventral, dorsal or lateral surface of the urethra: are results affected by the surgical technique?使用置于尿道腹侧、背侧或外侧的颊黏膜移植物进行球部尿道成形术:手术技术会影响结果吗?
J Urol. 2005 Sep;174(3):955-7; discussion 957-8. doi: 10.1097/01.ju.0000169422.46721.d7.
6
On the art of anastomotic posterior urethroplasty: a 27-year experience.论吻合性后尿道成形术的技巧:27年经验
J Urol. 2005 Jan;173(1):135-9. doi: 10.1097/01.ju.0000146683.31101.ff.
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Cross-cultural adaptation and validation of the English version of the International Index of Erectile Function (IIEF) for use in Malaysia.国际勃起功能指数(IIEF)英文版在马来西亚的跨文化调适与验证。
Int J Impot Res. 2003 Oct;15(5):329-36. doi: 10.1038/sj.ijir.3901009.
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Failed posterior urethroplasty: lessons learned.后尿道成形术失败:经验教训
Urology. 2003 Oct;62(4):719-22. doi: 10.1016/s0090-4295(03)00573-9.
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Reconstruction of posterior urethral disruption injuries: outcome analysis in 82 patients.后尿道断裂伤的重建:82例患者的结果分析
J Urol. 1997 Feb;157(2):506-10.
10
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Zhonghua Wai Ke Za Zhi. 1988 Sep;26(9):565-7, 575.